Virus Like Particles: Nanoparticles for Targeted Drug Delivery
Virus Like Particles: Nanoparticles for Targeted Drug Delivery
Khaled A. El-Dougdoug1, Wael S. El-Araby2* and Rehab, A. Dawoud3
ABSTRACT
Virus-like particles (VLPs) are biological entities at the nanoscale level that are made of viral proteins organized in a morphology that resembles the original virion but lacks the viral genetic material. VLPs are appealing as a system because their proteins can be altered both chemically and genetically, opening up a wide range of potential uses. Virus-like particles (VLPs) are ideal for antigen and medication administration because viruses are strong immune activators and efficient vectors for transporting genetic elements into host cells. Recent developments in VLP platform engineering, activation, and release strategies, in addition to their application to drug administration, are discussed. The utilize of VLPs for drug delivery in model systems is discussed, and various examples of its effectiveness are highlighted.
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July 2023
Vol. 11, Iss. 2
