The Epidemiology of Enterobiasis and Molecular Characterization of Enterobius vermicularis in Children of Karachi, Sindh, Pakistan
The Epidemiology of Enterobiasis and Molecular Characterization of Enterobius vermicularis in Children of Karachi, Sindh, Pakistan
Syeda Batool Zehra1, Abdullah G. Arijo2, Aly Khan3, Nasira Khatoon1* and Samina Waheed1
ABSTRACT
Pinworms (Enterobius vermicularis) belong to the Oxyuridae family which cause enterobiasis, under unsanitary conditions, the Oxyruidae family causes health concerns, particularly in children. Samples were collected from the laboratory of Jinnah Hospital, Karachi, Sindh, Pakistan. The data of 60 pinworm-infected children were recorded. These children were of various sexes and ages. Pinworm prevalence in children by gender from 2019 to 2020 demonstrates that females have a higher rate of incidence than males because of unsanitary circumstances and hormone production. Traditional pinworm diagnosis via PCR for pinworm detection has been performed. The findings in this research were based on two key factors: molecular analysis and statistical analysis. When traditional morphological techniques used with, molecular biology technologies it has proven to be effective in distinguishing closely related species. Statistical analysis is used to determine the intensity of infection in relation to age and gender. This study will focus on children who are suspected of being afflicted with pinworms. The presence of adult worms or ova in the feces is required to make proper diagnosis. The swabbing of the perianal region is utilized to determine the presence of eggs in feces.
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