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Regulatory Effect of Angelica sinensis Polysaccharide on BMP-7/Smads/TGF-β1 Signal Pathway in Kidney of Rats with Radiation Injury

Regulatory Effect of Angelica sinensis Polysaccharide on BMP-7/Smads/TGF-β1 Signal Pathway in Kidney of Rats with Radiation Injury

Xiaowei Huang1, Jinji Wang1, Zhun Yu2, Minghua Duan1* and Zhe Lin1*

1School of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China
2The Third Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130117, China
 
* Corresponding author: duanduan-2007@163.com, linzhe1228@163.com

Fig. 1.

Body weight changes of ASP on SD rats and effects of ASP on NOS and NO levels in serum. Values are expressed as means ± SEM. Notes: Compared with normal group: **p < 0.01, ***p < 0.001; compared with model group: #p < 0.05, ##p < 0.01. 

Fig. 2.

Effects of ASP on MDA and SOD levels in kidney.  ###p < 0.001. For statistical details, see Fig.1.

Fig. 3.

The effect of ASP on TGF-β signaling pathway in rat. For statistical details, see Figs. 1 and 2.

Pakistan Journal of Zoology

October

Vol. 54, Iss. 5, Pages 2003-2500

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