Interferon Status and Expression of P53 and gadd45g Genes in Leukaemogenic Felv Infection in Domestic Cats
Interferon Status and Expression of P53 and gadd45g Genes in Leukaemogenic Felv Infection in Domestic Cats
Alexander Tsybulsky1*, Tatyana Tabakaeva1, Anna Klimovich2, Michail Shchelkanov1, Eduard Kostetsky1, Maksim Aliev1, Anton Degtyarenko3
Figure 2
Differences in expression of interferon, p53 and gadd45g genes in blood leukocytes from group 2 cats relative to group 1.
Relative expression levels of target genes normalized by the gapdh. The values presented are quotients of the expression values in group 2 by the expression values in group 1 (Fold2 / Fold1).
Figure 3
Dependence of the leukaemic process activity and parameters that characterise the replicative activity of FeLV, the concentration of IFN in the blood and the expression of certain genes of the IFN system and the p53 and gadd45g genes.
Figure 1
Plasma IFN concentrations in group 1 and group 2 cats with leukaemogenic FeLV-infection.
Group 1 – cats with aleukaemic stage of leukaemia, group 2 - subleukaemic stage of leukaemia.
March 2022
Vol. 10, Iss. 3, Pages 451-711
