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Experimental Evaluation for Graviola Extracts and Eucalyptus Extract’s Capacity to Induce Healing of Hepatocytes in Rabbits Model

Experimental Evaluation for Graviola Extracts and Eucalyptus Extract’s Capacity to Induce Healing of Hepatocytes in Rabbits Model

Heba Saleh Shaheed1, Zainab J. Malik2*, Ghusoon A.A. Alneamah1, Salih T.H.2

1Department of Surgical and Obstetric, Collage of Veterinary Medicine, Al-Qasim Green University, Babylon 51013, Iraq; 2Department of Pathology and Poultry Diseases, Collage of Veterinary Medicine, Al-Qasim Green University, Babylon 51013, Iraq.

 
*Correspondence | Zainab J. Malik, Department of Pathology and Poultry Diseases, Collage of Veterinary Medicine, Al-Qasim Green University, Babylon 51013, Iraq; Email: [email protected]

Figure 1:

Gross section showed a midline laparotomy. In the upper abdomen, exposing the fourth lobe of the liver, a surgical incision was made to perform a partial liver resection in rabbits.

Figure 2:

Gross section showed handling by use  thump forceps and  revelation  of  the  third lobe of  liver a for doing partial hepatoctomy in rabbit.

Figure 3:

Gross section showed the base of the liver and near the inferior vena cava, sutures were tied over the liver lobe and surgical removed done for doing partial hepatoctomy in rabbit.

Figure 4:

Gross section showed grade II adhesion (MSAS) between the liver, omentum, and abdominal wall in the Graviola group (A) and Eucalyptus camaldulensis group (B).

Figure 5:

Histopathological section of   liver of  rabbit of Graviola group showed heavy inflammatory reaction infiltration in entire hepatic parenchyma (blue arrows) with  dilation of central veins (black arrow) (staining with H and E stain 10X).

Figure 7:

Histopathological section of a rabbit liver from Eucalyptus camaldolensis leaf group extract showed mild regeneration of hepatocyte of liver  (arrow) (staining with H and E stain 10X).

Figure 8:.

Histopathological section of liver related to treated group to extract of eucalyptus camaldulensis leaves, shows infiltrated  mononuclear cells (A) and appear of myofibroblast (B), with granulation tissue formation  (staining with H and E stain 10X.).

Figure 9:

Histopathological section The liver after returning to its normal structure, which is represented by hepatocytes cord around the central vein (arrow) (staining with H and E stain 100X).

Figure 10:

Histopathological section of liver related to Graviola  treated group, shows normal hepatic architecture which represented by normal lobules, CV (staining with H and E stain 10X).

Figure 6:

Histopathological section of  liver of  rabbit of eucalyptus camaldulensis extract of leaves group showed infiltration of  inflammatory cells (blue arrows) and  the bile duct is  dilated and surrounded by inflammatory cells (green arrows) in addition to the dilation there is congested of hepatic artery (black arrow), (staining with H and E stain 40X.)

Journal of Animal Health and Production

November

Vol. 12, Sp. Iss. 1

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