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Efficacy of Amoxicillin and or Enrofloxacin Against Mixed Infection with Escherichia coli and Salmonella enteritidis In vitro and In vivo

Efficacy of Amoxicillin and or Enrofloxacin Against Mixed Infection with Escherichia coli and Salmonella enteritidis In vitro and In vivo

Mai A Fadel1*, Ahmed M Elmahdy1, Jihan Mostafa Badr2, Mohammed AM Saleh3, Mona A.A. AbdelRahman3 

1Pharmacology and Pyrogen Unit, Biochemistry, Toxicology, Feed Deficiency Department, Animal Health Research Institute (AHRI), Agricultural Research Center (ARC), Dokki P.O. Box 246, Giza 12618, Egypt; 2Department of Poultry Diseases, Animal Health Research Institute (AHRI), Agricultural Research Center (ARC), Dokki P.O. Box 246, Giza 12618, Egypt; 3Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute (AHRI), Agricultural Research Center (ARC). Nadi El-Seid Street, Dokki P.O. Box 246, Giza 12618, Egypt.

*Correspondence | Mai A Fadel, Pharmacology and Pyrogen Unit, Biochemistry, Toxicology, Feed Deficiency Department, Animal Health Research Institute (AHRI), Agricultural Research Center (ARC), Dokki P.O. Box 246, Giza 12618, Egypt; Email: [email protected] 

Figure 1

Showed Statistical analysis of E coli count in 4 groups after treatment. 

Figure 2

Chromatogram of amoxicillin, enrofloxacin, and ciprofloxacin at concentration 0.5µg/ml. 

Figure 3

Mean serum levels of enrofloxacin versus the time course after a single oral dose at 10 mg/kg (Full dose) and 5mg/kg b.wt. (Half dose) in healthy and diseased broilers. 

Figure 4

Mean serum levels of Amoxicillin versus the time course after a single oral dose at 13.1mg/kg (Full dose) and 6.55mg/kg b.wt. (Half dose) in healthy and diseased broilers. 

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Advances in Animal and Veterinary Sciences

December

Vol. 12, Iss. 12, pp. 2301-2563

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