Effects of Naringenin on Cadmium-Induced Changes in Blood Physiological and Biochemical Indices and Kidney Damage Among Rats
Effects of Naringenin on Cadmium-Induced Changes in Blood Physiological and Biochemical Indices and Kidney Damage Among Rats
Lulu Ding, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Mengli Jiang and Jicang Wang*
Effect of naringenin on cadmium induced kidney injury in rats (H and E, 400×, scale bar = 50 μm). Kidney sections from control rats showed normal glomerular and tubular histomorphology. In the cadmium exposure group, the glomerulus was shrunk and the tubular structure was damaged. The structural damage of glomeruli and renal tubules was alleviated in Nar and Cd co treated group. (A) control group; (B) Cd-treated group; (C) Nar-treated group; (D) Cd + Nar-treated group.
The pathological scores of kidney tissues in different treatment groups were evaluated by members of the experimental group, and three independent experiments were repeated. *, indicates significant difference compared with the corresponding control (*P < 0.05). #, indicates statistically significant difference between the Cd and Cd + Nar groups (#P < 0.05).