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Characterization and Assessment of Antibacterial Potential of Garlic Based Silver Nanoparticles

Characterization and Assessment of Antibacterial Potential of Garlic Based Silver Nanoparticles

Mehwish Saleem1* and Amina Atiq2

1Lahore College for Women University, Lahore, Pakistan; 2Islamia College Cooper Road, Lahore, Pakistan.

 
*Correspondence | Mehwish Saleem, Lahore College for Women University, Lahore, Pakistan; Email: [email protected]

ABSTRACT

Garlic nanoparticles are inexpensive, harmless, easy to use and eco-friendly. In this study, silver nanoparticles based on inexpensive garlic clove extract were created, and their all-around antibacterial effectiveness was assessed. To create garlic clove extract-based silver nanoparticles, 100 ml of distilled water was combined with 0.01g, 0.025g, and 0.05g extracts of both aqueous and ethanol to create 0.01%, 0.025%, and 0.05% extract solutions, respectively. All of these extracts were then mixed with silver nitrate to create a 0.01M solution of silver nitrate nanoparticles. UV-VIS was done for the characterization of the nanoparticles. Various bacterial strains were successfully combatted by garlic nanoparticles’ strong antibacterial properties (E. coli, Klebsiella pneumonia, Bacillus subtilis and Staphylococcus aureus). Additionally, Staphylococcus aureus showed the greatest sensitivity to garlic nanoparticles, with inhibitory zones of 19 mm, 17 mm, and 18 mm for an aqueous extract for aqueous extract and for ethanolic garlic extract was (19mm, 17mm and 15mm) K. pneumonia was the least susceptible, with inhibitory zones for aqueous and ethanolic garlic extracts of 10 mm, 9 mm, and 11 mm, respectively (10mm, 8mm and 10mm). The findings of the study point to the potential for supplementing antibiotic therapy with garlic, which may improve antibiotic efficacy.

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Journal of Innovative Sciences

December

Vol.9, Iss.2, Pages 192-241

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