Association of Chemokine Genes CXCL9 and CXCL10 Polymorphisms with Tuberculosis in Pakistani Population
Association of Chemokine Genes CXCL9 and CXCL10 Polymorphisms with Tuberculosis in Pakistani Population
Saleha Tabassum1, Muneeza Zafar1,2, Munazza Raza Mirza1*, Muhammad Iqbal Choudhary1,3, Ikram ul Haq4, Imran Riaz Malik2, Ambreen Ansari1 and Mehtab Alam5
(A) Tri-ARMS PCR assay based genotyping of CXCL10 rs5606198 (G/A) polymorphism on 2.5% agarose gel. Lane L shows 1000 bp molecular marker, lane 1 and 2 shows positive control with GA genotype. Lanes 3, 4 and 5,6 represents GA genotype with band size of 545 and 295bp. (B) T-ARMS PCR assay based genotyping of CXCL9 rs2276886 (G/A) polymorphism on 2.5% agarose gel. Lane L shows 1000 bp molecular marker, lane 1 shows positive control. Lanes 3, 4 and 5 shows GG genotype of 232 bp along with control band of 595 bp. Lanes 1, 7 represent GA genotype with both bands of 4081 bp and 232 bp along with control of 595 bp. Lane 2 represents AA genotype with both bands of 408bp and 595bp.
