Fang Wang, Yong-Fang Jia, Po Wang, Qi-Yan Du and Zhong-Jie Chang*
...to detect the effects of letrozole on gonad differentiation, 5dph fry of carp were exposed to different concentrations of LET. At 130 dph, sex ratio was recorded. The results showed that continuous exposure to LET induced the changes of sex ratio. High concentration of LET can promote male-biased sex ratio. In order to reveal the molecular mechanism by which LET caused sex reversal, juvenile carp (120dph) were exposed to 0, 5, 25, 125, and 625μg/L LET for 1...
Sadaf Ghulam Rasul1*, Uzma Yaqub2, Maida Manzoor1 and Hafsa Mubasshar1
Hind A.Norii1, Adel M.Hassen ALZobidy2*
...reproductive hormones in letrozole-induced PCOS induced by letrozole in adult female rats. The negative control received 1 ml of 0.5% carboxymethyl cellulose (CMC) whereas positive control animals received 1 mL of 0.5% CMC (carboxymethylcellulose). Three treatment groups were treated with either the VAC vitex agnus castus extract (150 mg/kg bw or 250 mg/kg bw or 1 mg/kg bw) orally. The result showed an increased in body weig...
