Gökhan Kuş1,*, Hatice Mehtap Kutlu2, Djanan Vejselova2 and Emre Comlekci3
...umor cells when produced endogenously in the cells or applied exogenously. Ceramidases, which are main component of ceramide pathway catalyze metabolism of proapoptotic ceramide to anti-apoptotic sphingosine and other fatty acids. In this study we have evaluated the pro-apoptotic effect of ceranib-2, a human ceramidase inhibitor and of a short-chain C2 ceramide on human lung adenocarcinoma cells, A549 by determining cytotoxicity of these agents by trypan blue ...
Jia-xiang Wang1,2,* and Peng Li1,2
...: justify;">Ghrelin, the endogenous ligand for the growth hormone secretagogue receptor, has been identified in the pancreas of many vertebrates. While ghrelin has been found in the cerebellum and gastrointestinal tract of African ostrich chicks, little is known about its distribution in the pancreas ofthe African ostrich. In the present study, the distribution and morphological characteristics of ghrelin-immunopositive cells in the African ostrich pancreas we...
LX Ye1,2, JX Wang1,2,*, P Li1,2 and XT Zhang1,2
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Xiaoting Zhang1,2, Jiaxiang Wang1,2,*, Peng Li1,2,* and Lixun Ye1,2
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Tayfun Karataş
...acting substance levels, endogenous reserves in liver and muscle tissues of rainbow trout (Oncorhynchus mykiss). Eight-days of fasting caused a significant decrease in glucose, total protein, triglyceride, cholesterol, high-density lipoprotein and low-density lipoprotein levels as well as protein and lipid reserves in liver and muscle tissue of fish (p<0.05). The fasting period had no significant effect on the hepatic thiobarbituric acid reactive sub...
Aisha Siddiqua1*, Munir Ahmad1 and Nusrat Habib2
Ping Jiang1 , Zhihui Zhao1, 2, Xiaohui Li2, Mengyan Wang2, Lixin Xia2, Yang Cao3, Runjun Yang2 and Xibi Fang2*
...expression levels of the endogenous gene ABCA1 in bovine mammary epithelial cells (BMECs) to analyse the effect on intracellular triglyceride (TG) content by quantitative real-time polymerase chain reaction (qRT-PCR), Western blot, cell TG Assay and RT2 Profiler PCR array. The results showed that ABCA1 knockdown reduced the TG content in BMECs. On the other hand, the RT2 Profiler PCR array demonstrated that the expression levels of 12 g...
Asim Faraz1*, Abdul Waheed1, Muhammad Mudasser Nazir2, Aneela Hameed3, Nasir Ali Tauqir4, Riaz Hussain Mirza1, Hafiz Muhammad Ishaq1, Rana Muhammad Bilal5
... exogenously or secreted endogenously, establishes in minutes the desired effects and metabolized to inactive products rapidly in the body. Irrespective of whether OT is ingested with milk or secreted into the milk, it is degraded readily by gut-enzymes so that it doesn’t reach the circulation in biologically-active form so there seems to be less or no harm in consumption of milk from OT-treated-animals. But OT has remarkable effects on milk quality, com...
Tingting Li, Shuangshuang Geng, Long Xie, Huiyan Xu, Aolin Luo, Pengwei Zhao, Huan Yang, XingWei Liang, YangQing Lu, XiaoGan Yang* and KeHuan Lu*
...nimals. However, whether endogenous GDNF is superior to xenogenic GDNF in SSC culture in vitro remains unclear. To answer this question, the buffalo GDNF gene was cloned and integrated into the PiggyBac eukaryotic expression vector, which was stably expressed in Sertoli cells, thus establishing a PB-GDNF-Sertoli cell line. Quantitative real-time polymerase chain reaction (qRT-PCR) results showed that the GDNF gene expression in the PB-GDNF-Sertoli cell ...
Yang Yang1,2, Ji Shao1,2, Mingxu Zhou3,4, Qiangde Duan1,2, Xinyi Zhang1,2 and Guoqiang Zhu1,2*
...owed with the ability of endogenous synthesis of 3OC12-HSL and C6-HSL. At the same time, 200 μmol/L 3OC12-HSL and C6-HSL were added into the culture medium, respectively, and co-cultured with ETEC strain C83902. ETEC strains were stimulated by exogenous and endogenous long-chain and short-chain AHL molecules, respectively, and their biological characteristics, such as growth characteristics, biofilm formation ability, and...
Jiao Ma*
...rtant role in increasing endogenous cardiac stem cell proliferation and migration capacity. One of the successful approaches is to use these factors along with cardiac stem cells to boost the repair efficiency of heart injury. Therefore, in the present review study, the types of cardiac stem cells and their molecular phenotype, cardiac stem cell genetics and their ability to treat heart injury have been studied. Understanding the molecular processes and messag...
Muhammad Tariq1, Imtiaz Rabbani2, Muhammad Shahbaz Yousaf2, Imdad Ullah Khan1*, Hafsa Zaneb2, Sajid Iqbal3, Alam Zeb Khan1, Shakirullah1, Muhammad Shuaib Khan1, Atta Ur Rehman1 and Mumtaz Ali Khan2
... damages the spermatozoa endogenously. These stresses can be controlled with the inclusion of antioxidants in semen extender at the time of cryopreservation. In the current study, semen from four (n=4) healthy Nili Ravi buffalo bulls was collected through artificial vagina and Gallic acid was added to the semen at 1 µM, 15 µM, 30 µM, 45 µM, 60 µM, and 100 µM. A total of six groups were prepared. One group was kept as control...
Chinar Mustafa Mohammed1*, Thamer M. Bashir1, Omar A.M. Al-Habib2, Farhad Ramadhan1, Mohammed Bassam1
...;">Taurine, a ubiquitous endogenous sulfur-containing amino acid, possesses numerous pharmacological and physiological actions, including antioxidant activity, modulation of calcium homeostasis, and antiapoptotic effects. There is mounting evidence supporting the utility of taurine as a pharmacological agent against heart disease, including chronic heart failure. This study investigated the potential protective effects of taurine, on behavior and cardiovascula...
Muhammad Akram1*, Muhammad Imtiaz Shafiq2, Amber Malik3, Farmanullah Khan4, Munir Ahmad Bhinder5 and Muhammad Sajjad6
...fense mechanisms include endogenous glutathione concentration, superoxide dismutase, catalase, and glutathione S-transferase (GST). GST neutralizes reactive oxygen species to regulate physical homeostasis in the body. The target of this study was to evaluate the molecular role of GST genotypic polymorphism involved in the development of CVD. For this case-control study, a total of 504 participants including 261 CVD patients and 243 healthy individuals were enr...
Muhammad Jan1*, Muhammad Ashraf Sumrah1, Javed Iqbal2, Muhammad Aslam3, Rizwan Latif4, Muhammad Arif5, Muhammad Tahir Akbar6 and Hafiz Husnain Nawaz1
...tic variability and some endogenous hormonal balance. Alternate bearing results into poor flowering, low pollination, low fruit set and fruit drops. All these factors are the climatic factors dependent which can be controlled by proper irrigation scheduling, proper pruning and proper dose and source of fertilizer application at a proper growth stage. As a result, OFF season crop in once year and followed by ON year crop. Alternate bearing cannot be completely ...
Doaa H. Assar1, Rasha A. Al Wakeel2, Mahmoud M. El-Maghraby3, Mohammed M. El-Badawy3, Adel A. El-Badawy3, Wael M. Nagy3, Mustafa S. Atta2, Abdel-Khalek E. Abdel Khalek4*
...adicals by enhancing the endogenous antioxidant enzyme activities, metabolism, immunity, and reproduction.
Keywords | Allicin, Antioxidative enzymes, Healthy status, Immunity, milk, Lambing rat.
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Doaa H. Assar1, Rasha A. Al-Wakeel2, Zizy I. Elbialy3, Mahmoud M. El-Maghraby4, Helmy K. Zaghlool5, Adel A. El-Badawy4, Abdel-Khalek E. Abdel-Khalek6*
Siswanto Imam Santoso*, Agus Setiadi, Wahyu Dyah Prastiwi
...ogy, and production; the endogenous variable was sustainability. Structural equation modeling (SEM) using TETRAD-IV software was employed to establish the analytical model. The results show that duck farming is sustainable regarding social, economic, and environmental aspects. Medical and technological factors significantly affect production. Social factors, egg processing, technology, and production significantly affect sustainability. To improve the sustaina...
El-Dougdoug. K.A.1, Mervat, M. Fath Alah2, Reham A. Hassen3,Rehab A . Dawoud2
...tance (the high level of endogenous salicylic acid, protein content, chlorophyll contents and peroxidase and polyphenol oxidase activities as well as 
increasing in growth parameters).
... increasing in growth parameters).
M.A. Abo-EInasr l, Kh.A. EL-Dougdougl, M.H. El-Kattan2 and L.A. Salem2
... i.e., the high level of endogenous salicylic acid, proteins related to inducers and activity of peroxidase and chitinase enzymes. Salicylic acid (0.5%) and potassium sulfate (3%) gave the highest effect in inducing SAR. where the treatment with them had forbid disease symptoms, and virus concentration was (0), 25 days post inoculation. In addition, the biochemical changes reached to the maximum values. whereas other chemicals gave a medium ability to induce S...
Ping Sheng Ye1, Lin Li2, Yu Long Wu3 and Yuan Shu Zhang1*
... evaluate the effects of endogenous GH-IGF-1 axis on lactating goats fed with high-concentrate diets. Ten lactating goats were used and randomly divided into two groups, in a 2×2 Latin square experiment design with different forage to concentrate rations of 40:60 (the control group) and 60:40 (the high-concentrate group), respectively. During the experiment, milk samples were collected to assay the content of milk compositions; plasma samples were collec...
Noura K. Al-Suwailem1, Nancy N. Kamel2, Ahmed O. Abbas1,3*, Farid S. Nassar1,3 , Dalia A.A. Elsayed4, Gouda F. Gouda1,5, Hosam M. Safaa6
...tage, albumin level, and endogenous antioxidant activity. Meanwhile, plasma total protein, cholesterol, triglycerides, creatinine, urea levels, and liver enzymes activity were significantly (P<0.05) increased. The carcass yield and meat quality showed significant (P<0.05) deterioration in response to heat exposure. MLM administration to the basal diet significantly enhanced blood metabolite levels, hematological parameters, antioxidant activities, carcas...
Khalid Hussain*, Tanvir Hussain, Zahid Rauf and Nowsherwan Zarif
...omehow responsive to the endogenous and biological factors as well. Strong and significant relationship was found between diameter and age. Time series revealed a drought period spanned between 1760-1950 CE; however, beyond 1950 CE uptrend in growth which remain constant upto the years 2000 CE. Species may be used to study climatic variations and reconstruction of the past climate and predictions of future changes....
Syed Fazal Baqi Kakakhel
... of the valley use their endogenous knowledge for collection, drying, packing and marketing. Questionnaire of standard questions was designed and data regarding five years back record, recent information on collection in the beginning of summer season and at the end of summer season was investigated and asked about the total quantity of morels (Species wise) collected from the study area. The local people use traditional techniques of collection, drying, stori...
Suhair Sh. Al-Siraj1, Jihan M. Badr2 and Dalia M.A. El-Masry3*
... Mcr1 genes) compared to endogenous genes (16s rRNA). As conclusions: The plant extracts and nanoemulsion may prevent pathogenic microorganism-induced deterioration and provide antibacterial agents for gram-positive and gram-negative bacterial infections.
Keywords | Plant extract, Bay leaf, Nanoemulsion, Antibacterial, Pathogenic bacteria, Gene expression, Resistance
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