Search for Carvacrol

The Restorative Effect of Titanium Dioxide Nanoparticles Synthesized with Origanum vulgare L., Carvacrol, Hypericum perforatum L., and Hypericin Loaded in Calcium Alginate Scaffold on Staphylococcus aureus-Infected Ulcers in Diabetic Rats

Dhiya Altememy1, Mohammad Darvishi2*, Samira Shokri3, Saber Abbaszadeh4

...d with Origanum vulgare, carvacrol, Hypericum perforatum, and calcium alginate scaffold-loadable calcium alginate on infected wounds with Staphylococcus aureus was investigated in diabetic rats. Eight groups of 12 rats in any group were diabetic by intraperitoneal injection of alloxan. After the rats were anesthetized, 2cm2 wounds were created and inoculated with bacterial suspension of S. aureus (ATCC 12600) equivalent to the 0.5 MacFarland tube. The hydroalc...

Enhanced Antitumor and Anti-Metastasis Efficiency via Combined Treatment with Carvacrol and Doxorubicin

Hu-Hu Chen^1,2, Xin Li^2,3, Mohd Hijaz Mohd Sani² and Siat Yee Fong^2,4*

...th doxorubicin (Dox) and carvacrol on proliferation, apoptosis, migration and invasion of MDA-MB-231 cells. After co-treatment with varying concentrations of Dox and carvacrol, cell proliferation, migration, and invasion were assessed. The expression levels of proteins associated with associated with the observed effects were measured through Western blotting. The results showed that, co-administration of Dox and

Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway

Hu-Hu Chen^1,2*, Jiao-han Zhou³ and Siat Yee Fong^2,4

...vestigated the effect of carvacrol on cell viability, cell cycle progression, and apoptosis in Dox-resistant triple negative breast cancer (TNBC) MDA-MB-231/Dox cells. Western blotting analyses were performed to access protein levels associated with apoptosis and the PI3K/Akt pathway. The results revealed that carvacrol significantly inhibited MDA-MB-231/Dox cell proliferation in a concentration-dependent manner compared to ...