Articles
183 open-access articles · page 3 of 10
Research ArticleBio-screening of Chalcone and Aurone analogues as therapeutic agents
MUHAMMAD MANSHA, QAMAR ALI, UROOJ FATIMA DILAWARI, ABRAR HUSSAIN, MUHAMMAD TARIQ
Chalcones and aurones are compounds having appealing pharmacological profile due to presence of carbonyl system. The bio-screening of 13 compounds was conducted and assessed against S. aureus, C. albicans and E. coli by agar well diffusion method. Chalcones an…
27 Feb 2024- Research Article
Fluidic simulation for blood flow in five curved spiral microchannel
MUHAMMAD JAVAID AFZAL, FARAH JAVAID, SHAHZADI TAYYABA, ANEEQA SABAH, MUHAMMAD WASEEM ASHRAF
This study presents ANSYS FLUENT and Fuzzy Logic MATLAB simulation for the study of blood flow in five curved spiral shaped tortuous vein. The dimensions of spiral microchannel used in simulation are 30 mm long and 2 mm in radius. ANSYS simulation has given 0.…
27 Feb 2024 - Research Article
Assessment of Roadside Soil and Brassica Rapa Contamination by Heavy Metals in District Buner, Pakistan
MUJIBUR RAHMAN, MUHAMMAD AYAZ KHAN, WISAL SHAH, ALIA NAZ
This study was conducted in Buner district of Pakistan to investigate the presence of Cadmium (Cd) and Lead (Pb) in roadside soil and Brassica rapa (Shalgham). For that purpose, soil and B. rapa samples were collected from primary, secondary, tertiary roadside…
27 Feb 2024 - Research Article
Optimization of sporulation conditions of Bacillus sublilis as potential probiotics strain
MUHAMMAD SHRAFAT ALI, UZMA HAMEED, IKRAM-UL-HAQ
Probiotics are used as a substitute for antibiotic growth promoters in the chick industry. In the present study, conditions for the sporulation of Bacillus subtilis, a probiotic strain, are optimized. Overnight grown inoculum (1%) was used for the cultivation…
27 Feb 2024 - Research Article
Genetic evaluation of tumor necrosis factor-alpha gene polymorphisms with pre and post term births
UZMA PARVEEN, MASROOR ELLAHI BABAR, NIDA BABAR, TAHIRA MUGHAL, AKHTAR ALI
Tumor necrosis factor alpha is known as multifunctional cytokine component of apoptosis and cell survival. Preterm delivery is a confused prenatal unfavorable occasion. This examination work was planned to associate relationship of G308A and -238 polymorphisms…
27 Feb 2024 - Research Article
Isolation and screening of keratinase producing bacteria from soil
MARIAM AHMED, YESRA ARSHAD, HAMID MUKHTAR
Keratinase (E.C 3.4.99.11) is an extracellular protease having efficient ability to degrade keratin found in feathers and hair. It has various applications including leather, textile, pharmaceutical, detergent and animal feed industries. In current study, kera…
27 Feb 2024 - Research Article
Simulation of a Nanoneedle for Drug Delivery by Using MATLAB Fuzzy Logic
MUHAMMAD JAVAID AFZAL, FARAH JAVAID, MUHAMMAD WASEEM ASHRAF, SHAHZADI TAYYABA, MAMOONA ASHIQ, AYESHA AKHTAR
The emerging technology of nanoneedle employ the nanoneedle for the penetration in cell membrane to investigate and manipulate biomedical procedures in the living cells. This study presents a simulated methodology on the basis of fuzzy logic for flow rate of d…
27 Feb 2024 - Research Article
Sex determination through Barr bodies of neutrophils in Humans and Dogs
MUSHTAQ HUSSAIN LASHARI, RABIA HAMEED, UMER FAROOQ, MUSADIQ IDRIS, ZIA UR REHMAN
Blood samples of healthy adult humans (n = 40) and dogs (n = 30) grouped as males and females, were collected aseptically through appropriate measures. Thin blood smears were stained using Field stain ‘A’ and ‘B’. The PMNs were counted…
27 Feb 2024 - Research Article
Heavy metals (Cd, Pb & Zn) accumulation in Cauliflower (Brassica oleracea. Var. Botyris) and associated health risks assessment in three Districts of Punjab, Pakistan
ZEESHAN REHMAN, RANA ABRAR HUSSAIN, SHAISTA JABEEN, SAKHAWAT ALI, ZAHAR NOREEN, IRUM MUKHTAR
Continuous discharge of untreated urban and industrial waste water is a source of heavy metals in soil is a major threat to ecological system and human health. Present study was carried out to evaluate human health risks in association with food chain contamin…
27 Feb 2024 - Research Article
Enhanced Sodium Chloride disturbs the Genetic stability in Ocimum tenuiflorum L.
MUBEEN RIAZ, KIRAN ZAHID, SUMAIRA ASLAM CHOHAN, MUHAMMAD ASHFAQ, MUHAMMAD ALI, RIFFAT SIDDIQUE et al.
The present investigation was carried out to evaluate the effects of NaCl stress on genetic stability of lines of Ocimum tenuiflorum L. using RAPD markers. For genetic characterization of controlled and NaCl stressed plants, the extracted DNAs were subjected t…
27 Feb 2024 - Research Article
Effect of Alloxan on IL-6 Gene Expression in Mus musulus
SYED SHAHID IMRAN BUKHARI, IQRA AZAM, MUDDASIR HASSAN ABBASI, MEERAB DAUD, NADEEM SHEIKH, ANDLEEB BATOOL et al.
Alloxan monohydrate is an organic compound with heterocyclic skeleton; it has been the routine part of all bakery products such as pizza, biscuits and cakes etc. Swiss albino mice of six weeks were divided into control group and experimental group. Experimenta…
27 Feb 2024 - Research Article
In vitro efficacy of Tribulus terretris L. & Ziziphus mauritiana Lam. as potential anthelmintics against Haemonchosis contortus
ABRAR HUSSAIN, AQSA KHALIL, SAIRA ZAHEER, MUHAMMAD LATEEF, MUHAMMAD MANSHA
Ruminants are common victims of helminthic infections which curb the efficient production of livestock. Chemical anthelmintic are used to control parasitic infections but their persistent use develop resistance in parasites. In this connection local plants/ th…
27 Feb 2024 - Research Article
Impact of Air Pollution on Growth of Lichens in Miandam Valley Swat, Pakistan
ASADULLAH KHAN, MUHAMMAD AYAZ KHAN, ALIA NAZ, ABDULLAH KHAN, NAUREEN AURANGZEB
This study was conducted to determine heavy metals i.e. Lead (Pb) and Cadmium (Cd) concentrations in lichen along different roads having varied traffic density and to find impact of the metals on its growth in Miandam valley Swat, Pakistan. Dermatocarpon minia…
27 Feb 2024 - Research Article
Floral and edaphic data recorded from Sahiwal District, Pakistan analyzed by multivariate techniques
ARIFA ZEREEN, ALMAS JAHAN, SHEIKH SAEED AHMAD, ZAHEER-UD-DIN KHAN
The current exploration was focused to study vegetation and environmental parameters associated with Sahiwal district. For the phytosociological survey Braun-Blanquet’s methodology was employed. In order to classify the vegetation data, ordination resear…
27 Feb 2024 - Research Article
Bacterial Exopolysaccharides: sources, production and applications
MARIAM ZAHEER, SYED SHAHID IMRAN BUKHARI, MUDDA
Exopolysaccharides (EPSs) are secreted by both eukaryotes (fungi, phytoplankton, and algae) and prokaryotes (archaeobacteria and eubacteria). EPSs produced by bacteria include a broad range of chemical structures and may either be heteropolymeric or homopolyme…
27 Feb 2024 - Research Article
Bacterial urinary tract infections and their association with age, gender and socioeconomic status
SIDRA MOQADDES*¹, RABIA ZULFIQAR, MAWRA GOHAR, HINA QAISER
Urinary tract infections are among common health issues worldwide. A large number of pathogens can colonize urinary tract due to enriched chemical composition of urine making it favorable for microbial growth. Current study was designed to investigate bacteria…
27 Feb 2024 - Research Article
Seasonal variations of invertebrates diversity & environmental health in intertidal area at Tak Bay, (Kalatoo) Hingol National Park Balochistan Pakistan
ATEEQUE RAHMAN KHOOHARO, PIRZADA JAMALUDDIN A. SIDDIQUI
This study was initiated to discover the distribution & diversity of invertebrate communities on a rocky intertidal shore at Tak Bay, Ormara along the Balochistan coast of Pakistan. Quadrat techniques were used to establish abundance of species. Overall, 4…
27 Feb 2024 - Research Article
Azurin: A Hardcore Anti-Cancer Agent
ASMA ZAFAR, MONIBA KHAWAR, MAHNOOR CHAUDHRY, SAYYEDA SANA BATOOL, AMJAD HUSSAIN, MUSHTAQ AHMAD SALEEM
Cancer is a life-threatening disease which is emerging as a major problem in the field of medicine. Different methods are being used to eradicate cancer including chemotherapy, radiotherapy, immunotoxins, and drug therapy but these treatments cause various sid…
27 Feb 2024 - Research Article
Histopathological and Micrometric studies of Diazinon exposure on Thyroid and Parathyroid Tissues in Mice
SYEDA NADIA AHMAD, MEHWISH NASIR, AQSA NAUREEN, SHAGUFTA ANDLEEB, KAUSAR RAEES, TAHIR ABBAS et al.
Effects of Diazinon (DZ) were studied at 0, 2.5, 5, 10 and 20 mgkg-1 in adult male mice (10 in each dose group) for thyroid and parathyroid histopathology. Tissues were recovered following 48 h of DZ treatment. Micrometric data in terms of follicular size of t…
27 Feb 2024 - Research Article
Effect of selected organic amendments on germination and yield of Abelmoschus esculentus (L.) moench grown under Chromium stress
ALIA NASEEM, SUMERA IQBAL, KHAJISTA JABEEN
Okra (Abelmoschus esculentus (L.) Moench) was used as test crop in a research trial to assess the impact of organic amendments (compost and farmyard manure) on germination and yield under application of chromium (Cr) stress. The no. of treatments applied was 1…
27 Feb 2024