Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

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Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Mohammed A. Almujtaba¹, Turky Omar Asar², Salma Naqvi³, Vikas Kumar⁴, Fahad A. Al-Abbasi¹, Abdulbasit I. Al-Sieni¹ and Firoz Anwar¹*

Author Affiliations

¹Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

²Department of Biology, College of Science and Arts, University of Jeddah, Jeddah, Kingdom of Saudi Arabia

³Department of Biomedical Sciences, Gulf Medical University, Ajman, United Arab Emirates

⁴Natural Product Discovery Laboratory, Department of Pharmaceutical Sciences, Shalom Institute of Health and Allied Sciences. SHUATS, Naini, Prayagraj, India

* Corresponding author: fanwar1@kau.edu.sa

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Fig. 1.

Effect of Zam water on plasma concentration of various parameters in Dox - induced cardiac remodeling. Values are given as mean + SD, n= 6; * represents significant difference from Dox control group (*p<0.05; **p<0.01; ***p<0.001).

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Fig. 2.

Heart histology image of random sample from (i) Normal control (NC) (ii) Zamzam Control (ZC) (iii) Dox-induced cardiac remodeling control (DC) group and (iv) Dox-induced cardiac remodeling control + Zamzam (DZ) groups. (A-H and E stained; 40 X, B- H and E stained; 20 X, respectively).

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December 2022

Vol. 54, Iss. 6, Pages 2501-3000

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Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

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Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Mohammed A. Almujtaba¹, Turky Omar Asar², Salma Naqvi³, Vikas Kumar⁴, Fahad A. Al-Abbasi¹, Abdulbasit I. Al-Sieni¹ and Firoz Anwar¹*

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Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Mohammed A. Almujtaba1, Turky Omar Asar2, Salma Naqvi3, Vikas Kumar4, Fahad A. Al-Abbasi1, Abdulbasit I. Al-Sieni1 and Firoz Anwar1*

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Mohammed A. Almujtaba¹, Turky Omar Asar², Salma Naqvi³, Vikas Kumar⁴, Fahad A. Al-Abbasi¹, Abdulbasit I. Al-Sieni¹ and Firoz Anwar¹*