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Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Zinc in Alkaline Water (Zamzam) Ameliorates Doxorubicin induced Cardiac Remodeling

Mohammed A. Almujtaba1, Turky Omar Asar2, Salma Naqvi3, Vikas Kumar4, Fahad A. Al-Abbasi1, Abdulbasit I. Al-Sieni1 and Firoz Anwar1*

1Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. 
2Department of Biology, College of Science and Arts, University of Jeddah, Jeddah, Kingdom of Saudi Arabia 
3Department of Biomedical Sciences, Gulf Medical University, Ajman, United Arab Emirates 
4Natural Product Discovery Laboratory, Department of Pharmaceutical Sciences, Shalom Institute of Health and Allied Sciences. SHUATS, Naini, Prayagraj, India
 
* Corresponding author: fanwar1@kau.edu.sa

Fig. 1.

Effect of Zam water on plasma concentration of various parameters in Dox - induced cardiac remodeling. Values are given as mean + SD, n= 6; * represents significant difference from Dox control group (*p<0.05; **p<0.01; ***p<0.001).

Fig. 2.

Heart histology image of random sample from (i) Normal control (NC) (ii) Zamzam Control (ZC) (iii) Dox-induced cardiac remodeling control (DC) group and (iv) Dox-induced cardiac remodeling control + Zamzam (DZ) groups.  (A-H and E stained; 40 X, B- H and E stained; 20 X, respectively).

Pakistan Journal of Zoology

October

Vol. 54, Iss. 5, Pages 2003-2500

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