Unveiling the Safety of Cassia alata Leaf Extract: A Subchronic Oral Toxicity in Rats
Unveiling the Safety of Cassia alata Leaf Extract: A Subchronic Oral Toxicity in Rats
Amaq Fadholly1,5*, Siti Sa’diah1,6, Diah Nugrahani Pristihadi1, Eva Harlina2, Maharani Kartika Ramadhan3, Yumna Annisa Kurnia Budiharjo4, Cyntia Rafi Adinugroho4, Afifah Alawiyah Rahmah4, Nahla Fifi Azizah4
Figure 1:
Mean body weight changes in male (a) and female (b) rats treated with CALE at dose levels of 0 (control), 100, 300, and 900 mg/kg/day for 28 days.
Figure 2:
Representative images of histopathologic changes in kidneys of male rats (A) and liver of female rats (B) in each dose group for 28 days of CALE administration. (a): control; (b): 100 mg/kg/day; (c): 300 mg/kg/day; (d): 900 mg/kg/day.
