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TGF-β Mediates the Role of P53 and microRNA-Related Signaling Pathways in the Pathogenesis of Diabetic Nephropathy in Rats

TGF-β Mediates the Role of P53 and microRNA-Related Signaling Pathways in the Pathogenesis of Diabetic Nephropathy in Rats

Yonghong Ma1, Jinlan Ma2, Qifu Zhang3, Huajie Zou1 and Shenghua Ma1*

1Department of Endocrine Metabolism, Affiliated Hospital of Qinghai University, Xining, Qinghai810000, China
2Department of Nephrology, Affiliated Hospital of Qinghai University, Xining, Qinghai810000, China
3Department of Trauma Orthopedics, Affiliated Hospital of Qinghai University, Xining, Qinghai810000, China
 
*      Corresponding author: [email protected]

Fig. 1.

Kidney histomorphology of rats in control (A) and experimental (B) groups (×400).

Fig. 2.

Expression of TGF- β1 and P53 (A and B) in the control group and TGF- β1 and P53 (C and D) in the kidney cortex of study groups (×400).

Pakistan Journal of Zoology

December

Pakistan J. Zool., Vol. 56, Iss. 6, pp. 2501-3000

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