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Study of Respiratory Tissue Engineering Model for Viral Infection and Bacterial Microbiome Interaction Under Physiological and Pathological Condition

Study of Respiratory Tissue Engineering Model for Viral Infection and Bacterial Microbiome Interaction Under Physiological and Pathological Condition

Ryan Septa Kurnia1* and Radiana Dhewayani Antarianto2
 

1Doctoral Program in Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta; 2Departements of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta.


*Correspondence | Ryan Septa Kurnia, Doctoral Program in Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta; Email: [email protected]

Figure 1:

Physiological condition of respiratory tract microbiome illustration. Diverse commensal bacteria in the respiratory tract live with a balanced composition without pathological conditions. Various pathogens (bacteria, viral and fungal) with relatively limited numbers are less likely to infect the host if there is no drastic changes in conditions. Glycocalyx is glycoprotein and glycolipid that cover the surface of the host epithelial cell membrane. Sialic acid which is in the structure has a place to attach to several normal microorganisms and pathogens which are assisted by sialoglycosidase.

Figure 2:

Bacterial community along the nasal cavity, pharynx, larynx, and trachea.

Hosts and Viruses

December

Vol.11, Pages 01-115

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