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Sappan Wood Ethanol Extract (Caesalpinia sappan L.) as Adjuvant and Substitute of Iron Chelator in Acute Iron Overload Rat Model

Sappan Wood Ethanol Extract (Caesalpinia sappan L.) as Adjuvant and Substitute of Iron Chelator in Acute Iron Overload Rat Model

Rezqita Putri Pitaloka1, Kartiawati Alipin1, Mas Rizky A.A Syamsunarno2, Gemilang Lara Utama3, Ramdan Panigoro2, Ratu Safitri1* 

1Department of Biology, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor, West Java 45363, Indonesia; 2Department of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Jatinangor, West Java 45363, Indonesia; 3Center for Environment and Sustainability Science, Padjadjaran University, Bandung, West Java 40132, Indonesia.

*Correspondence | Ratu Safitri, Department of Biology, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor, West Java 45363, Indonesia; Email: [email protected] 

Figure 1

Adjuvant serum iron level (A) and substituted serum iron level (B). Different letters between groups showed significant differences with 95% confidence level (p < 0.05). 

Figure 2

Adjuvant liver iron concentration (A) and substituted liver iron concentration (B). Different letters between groups showed significant differences with 95% confidence level (p < 0.05). 

Figure 3

Adjuvant cardiac iron concentration (A) and substituted cardiac iron concentration (B). Different letters between groups showed significant differences with 95% confidence level (p < 0.05). 

Figure 4

Adjuvant splenic iron concentration (A) and substituted spleen iron concentration (B). Different letters between groups showed significant differences with 95% confidence level (p < 0.05). 

Figure 5

Adjuvant renal iron concentration (A) and substitute renal iron concentration (B). Different letters between groups showed significant differences with 95% confidence level (p < 0.05). 

Figure 6

Adjuvant brain iron concentration (A) and substitute brain iron concentration (B). Duncan post-hoc test were not performed (p > 0.05). 

Advances in Animal and Veterinary Sciences

November

Vol. 12, Iss. 11, pp. 2062-2300

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