Presence of Neutralizing Antibodies to SARS-CoV-2 in Cats and Dogs Transported to Indonesia
Presence of Neutralizing Antibodies to SARS-CoV-2 in Cats and Dogs Transported to Indonesia
YP Arios1,2*, J Pamungkas3, IWT Wibawan3, D Iskandriati4, CS Tan5, SPH Rahman5, J Pamungkas3,4
ABSTRACT
A substantial number of studies have documented the presence of SARS-CoV-2 in dogs and cats through RNA and/or antibody detection, following the initial reported case of companion animal infection in March 2020. The transmission of SARS-CoV-2 from and to companion animals is crucial because dogs and cats frequently share close proximity with their owners and often engage with people and other animals outside of their household. Earlier research has suggested that pets can create an immune response to SARS-CoV-2; yet, it remains unclear whether the antibodies produced can effectively shield these animals against the virus. Data and studies regarding the presence of COVID-19 in dogs and cats in Indonesia and those being trafficked are useful to provide initial information on the presence of this disease, as no research has been conducted at all in Indonesia. This study was conducted to determine the existence of a specific immune response against COVID-19 in dogs and cats. Samples were taken from two exporting countries and clinics in Indonesia. Samples were tested using the species-independent Surrogate Virus Neutralization Test (SVNT). A total of 12 sera (8 cat serum and 4 dog serum), based on the results of the Surrogate Virus Neutralization Test analysis, formed antibody titers against SARS-CoV-2 in as many as four individuals (33.33%). The existence of protected antibody titers in dogs and cats can provide initial information for further studies.
Keywords | Antibody titer, COVID-19, Dogs and cats, SVNT
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