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Isolation of Nepetin (6-Methoxyluteolin) from Artemisia vulgaris and Spectroscopic Characterization: A Bioactive Flavonoid

Isolation of Nepetin (6-Methoxyluteolin) from Artemisia vulgaris and Spectroscopic Characterization: A Bioactive Flavonoid

Salim Saifullah1* and Achyut Adhikari2

1Chemistry Branch, Biological Science Research Division, Pakistan Forest Institute Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan; 2Central Department of Chemistry Tribhuvan University Kirtipur, Kathmandu, Nepal.

 
*Correspondence | Salim Saifullah, Chemistry Branch, Biological Science Research Division, Pakistan Forest Institute Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan; Email: [email protected]

ABSTRACT

Artemisia vulgaris, a medicinal plant with various pharmacological properties, has a longstanding history of global utilization. The biochemical components substantially impact the economy and pharmacological sector, providing various advantages. Nepetin, a flavonoid found in Artemisia plants, has been shown to possess various biological effects including anti-oxidant, anti-inflammatory, anti-cancer, and anti-apoptotic properties. In this study, nepetin as yellowish powder was isolated from A. vulgaris extract through column chromatography. Structure of the compound was elucidated through various spectroscopic techniques such as Mass and NMR (1D and 2D).

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Pakistan Journal of Forestry

June

Vol. 74, Iss. 1

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