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Intervention Effect of Total Glucoside of Paeony on Mesangial Proliferative Glomerulonephritis in Rats

Intervention Effect of Total Glucoside of Paeony on Mesangial Proliferative Glomerulonephritis in Rats

Xiujun Yao1, Haofeng Wang 2, Ligong Zhang3, Jingzhang Wu4 and Lijun Wang1*

1Departments of Paediatrics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong Province 250021, China.
2Departments of Combine Tracitional Chinese and Western Medicine, The Fifth Hospital of Jinan, 250000, China.
3Departments of Anesthesia, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong Province 250021, China.
4Urology Departmengt, Hengshui Peoples Hospital, Hebei Province 053000, China.

*      Corresponding author: nv1h58@163.com

Fig. 1.

Effect of total glucoside of paeony on 24 h urine protein quantity in different rat groups (n=10). *P<0.05, compared with the normal group. #P<0.05, compared with the model group.

Fig. 2.

Effect of total glucoside of paeony on kidney ROS (A), MDA (B), and SOD (C) content in the three rat groups after 12 weeks of intervention (n=10). *P<0.05, compared with the normal group. #P<0.05, compared with the model group.

Fig. 3.

Effect of total glucoside of paeony on kidney TGF-β1 (A) and CTGF (B) in the three groups after 12 weeks of intervention (n=10). *P<0.05,compared with the normal group. #P<0.05,compared with the model group.

Pakistan Journal of Zoology

June

Vol. 53, Iss. 3, Pages 801-1200

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