Curcuma Longa Methanolic Extract and Losartan Improves Memory Impairment and Oxidative Stress induced by a High Caloric Diet in Wistar Rats
Curcuma Longa Methanolic Extract and Losartan Improves Memory Impairment and Oxidative Stress induced by a High Caloric Diet in Wistar Rats
Sara Brikat, Mouloud Lamtai*, Miloud Chakit, Laila Ibouzine-Dine, Ilhame Fitah, Oumaima Abouyaala, Abdelhalem Mesfioui, Aboubaker El Hessni
Effect of High fructose diet on % of alternation of female rats measured in the Y-maze test. The data are presented as mean ± S.E.M. The significance level is 0.05 with * p < 0.05, ** p < 0.01, and *** p < 0.001.
Effect of High fructose diet on recognition memory performance of female Wistar rats evaluated in the OR test. The data are presented as mean ± S.E.M. The significance level is 0.05 with * p < 0.05, ** p < 0.01, and *** p < 0.001.
Behavioral performances of adult female rats in to the Morris Water maze. A – Escape latency during the acquisition phase expressed in seconds; B – The percentage of time spent in the target quadrant. The data are presented as mean ± S.E.M. The significance level is 0.05 with * p < 0.05, ** p < 0.01, and *** p < 0.001.
Effect of Curcumin and/or Losartan on levels of (A) thiobarbituric acid reactive substances (TBARS) and (B) nitric oxide (NO) and (C) catalase (CAT) activity in the hippocampus of female HFD-exposed rats. The data are presented as mean ± S.E.M. The significance level is 0.05 with * p < 0.05, ** p < 0.01, and *** p < 0.001.
