Comparative Therapeutic Evaluation of Partial Excision of Lesions and Administering Autogenous Vaccine along with Immune-Modulators for the Treatment of Bovine Papillomatosis
Comparative Therapeutic Evaluation of Partial Excision of Lesions and Administering Autogenous Vaccine along with Immune-Modulators for the Treatment of Bovine Papillomatosis
Muhammad Arif Zafar1, Murtaz-ul-Hasan1*, Aayesha Riaz1, Asim Shamim2, Muhammad Farooq Iqbal1 and Arfan Yousaf
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ABSTRACT
This study was conducted to evaluate therapeutic value of autogenous vaccine along with immune-modulators and to compare its efficacy with autogenous vaccine alone and partial excision of the lesions. To this end, nine animals were selected clinical and sporadic papillomas different body parts. These animals were divided into three groups; Group A animals were operated for partial excision of the lesions, Group B were inoculated with autogenous vaccine alone and Group C were treated with inoculation of autogenous vaccine supplemented with immune-modulators (Levamisole and Vitamin E+Selenium). The animals treated with autogenous vaccine along with immune-modulators showed complete regression of the papillomas compared animals, which were treated with autogenous vaccine alone. The partial excision of the papillomas showed no obvious differences. In conclusion, autogenous vaccine synergistically affected the immune-modulators (Levamisole and Vitamin E + Selenium) in complete regression of the papillomas. It is effective to use autogenous vaccine along with immune-modulators to revert the papillomas completely.
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