Clinical Features, Transmission Dynamics, Pathogenesis, and Diagnostic Approaches of Monkeypox Virus
Clinical Features, Transmission Dynamics, Pathogenesis, and Diagnostic Approaches of Monkeypox Virus
Yawar Abbas1, Muhammad Sajid2*, Musharraf Hussain3, Shahida Batool1, Saeed Ur Rehman1 and Jamil Ahmad1
ABSTRACT
Mpox virus is a double-stranded DNA virus within the Orthopoxvirus genus and Poxviridae family. The virus causes a zoonotic infection and shuttle between animal and human. The host spectrum of the mpox virus allowed evolutionary adaptation to a newer clade (Clade 1b) which appear to be more pathogenic and transmissible. While similar to smallpox virus, mpox virus was first reported in human during 1970 and since then remained endemic in Africa. First time in 2022, numerous cases were reported in various parts of Africa, as well as in the Northern and Western Hemispheres. Given the wider spread, changing dynamics and host spectrum, we aim to provide critical view of zoonotic nature of mpox virus in human, taxonomical position and signs of illness. Additionally, current research covers various diagnostic techniques for viral detection.
To share on other social networks, click on any share button. What are these?
