Assessment of the Spread of Certain Pathogens Among Laboratory Rodents at Universities and Academic Institutes of Almaty, Kazakhstan
Assessment of the Spread of Certain Pathogens Among Laboratory Rodents at Universities and Academic Institutes of Almaty, Kazakhstan
Rinat Islamov*, Dinara Turegeldieva, Altyn Rysbekova, Kuralay Sarmantayeva, Victor Semenuyk
ABSTRACT
The health of laboratory animals is one of the key components of ensuring the quality of research results. Microbiological status uncertainty creates risks not only for scientific research, but can also pose a danger to the researchers themselves. In this paper we present the results of the assessment of microbiological quality of laboratory animals from some universities and academic institutes in Almaty city, Kazakhstan. This is the first time that such work, involving several institutes, has been carried out. To do this, several pathogenic bacteria and viruses from the Federation of European Laboratory Animal Science Associations (FELASA) were selected. The main methods of testing biological samples from laboratory mice and rats were realtime polymerase chain reaction and enzyme-linked immunosorbent assay. A high prevalence of some pathogens among conventional laboratory animals used by some academic institutes and universities of Almaty has been shown. Rodentibacter pneumotropicus has been detected in the SPF animals, while no other pathogens from the FELASA list have been detected. The obtained results show the importance of not only regular health monitoring, but also the need to improve the quality of care and well-being of laboratory animals in some facilities of the Almaty city.
Keywords | Health monitoring, Mice, Rats, Rodent pathogens, Specific-pathogen free
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