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Antioxidant Role of Nano-Piperine and Ascorbic Acid in Some Blood Parameters and Liver in Dexamethasone Treated Male Rats

Antioxidant Role of Nano-Piperine and Ascorbic Acid in Some Blood Parameters and Liver in Dexamethasone Treated Male Rats

Saadeya Ali Lefelef Al-Gnami1, Fatima Ibrahim Mohammad2, Huda Jassim Mohammed Al-Helali3

1Physiology Department, College of Veterinary Medicine, University of Al- Qadisiyah, Al-adisiyah, Iraq; 2Pathological analyses Department, College of Science, University of Al- Qadisiyah, Al-Qadisiyah, Iraq; 3Veterinary Department, Al-Diwaniyah Veterinary Hospital, Iraq.
 
*Correspondence | Huda Jassim Mohammed Al-Helali, Dept. veterinary, Al-Diwaniyah veterinary Hospital, Iraq; Email: Hudaalhelali68@gmail.com 

The experimental periods have been accompanied by continuous monitoring of male rats. Dissecting the animals after the trial ended allowed us to measure RBCs, Hb levels, PCV, MCH and MCHC.Sample from liver was taken for histological study.

Figure 1:

UV visible spectrum of Piperine nano particles.

Figure 2:

FTIR spectrum synthesised Piperine nano particles.

Figure 3:

SEM images synthesized nano particles show cubic to triangle shape of about 33.8 nm.

Figure 4:

XRD analysis of Nano-Piperine.

Figure 5:

Section of liver tissues male rats drenched with distilled water (0.5 ml). (H&E)

Figure 6:

Section of liver tissues male rats drenched with Nanoparticle Piperine(15mg/kg suspended in 0.5 ml of distilled water).(H&E stain.40X).

Figure 7:

Section of liver tissues from male rats drenched with Vit. C (25mg/kg/B.W suspended in 0.5 ml of distilled water).(H&E stain.40X).

Figure 8:

Section of liver tissues from male rats drenched with Dexamethasone (2 mg/kg/B.W suspended in 0.5 ml of distilled water).(H&E stain.40X).

Figure 9:
Section of liver tissues from male rats drenched with Nanoparticle Piperine+ Dexamethasone ( suspended in 0.5 ml of distilled water).(H&E stain.40X).
Figure 10:

Section of liver tissues from male rats drenched with Vit. C + Dexamethasone (suspended in 0.5 ml of distilled water).(H&E stain.40X)

Pakistan Journal of Zoology

August

Pakistan J. Zool., Vol. 56, Iss. 4, pp. 1501-2000

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