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Antianemic Effect of Cyclosporine Loaded with Chitosan Nanoparticles on Induced Aplastic Anemia in Adult Male Dogs

Antianemic Effect of Cyclosporine Loaded with Chitosan Nanoparticles on Induced Aplastic Anemia in Adult Male Dogs

Essa D Alhtheal1*, Sufian S Salman2, Salah M AL-Kubaisi3

1Nanotechnology and Advanced Material Research Center, University of Technology-Iraq; 2Department of Veterinary Internal and Preventive Medicine, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq; 3Department of Veterinary Internal and Preventive Medicine, College of Veterinary Medicine, University of Fallujah, Al-anbar, Iraq.

 
*Correspondence |  Essa D Alhtheal, Nanotechnology and Advanced Material Research Center, University of Technology-Iraq; Email: [email protected]

Figure 1:

FE-SEM images of  chitosan nanoparticles.

Figure 2:

FE-SEM images of cyclosporine loaded chitosan nanoparticles.

Figure 3:

The cellularity of a bone marrow smear in PC group after induction of aplastic anemia by using of benzene.

Figure 4:

The cellularity of a bone marrow smear in T 3 group after treatment by cyclosporine -  loaded chitosan nanoparticles, which estimated as 30 %.

Figure 5:

Result of  Myeloid:Erythroid ratio.

Figure 6:

Result of RBC (1012/l).

Figure 8:

Result of  MCV.

Figure 9:

Result of  MCH.

Figure 10:

Result of  MCHC.

Figure 7:

Result of  Hemoglobin.

Advances in Animal and Veterinary Sciences

November

Vol. 12, Iss. 11, pp. 2062-2300

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