Alterations in Blood Cell Indices and Serological Parameters due to Toxicity of Industrial Leachate in Wistar Rats
Muhammad Babar Khawar1, Muddasir Hassan Abbasi2*, Zillay Mariam1, Nadeem Sheikh1,2*
1Cell & Molecular Biology Lab, Department of Zoology, University of the Punjab, Lahore, Pakistan
2Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan.
Figure 1:
Level of various electrolytes in sera. Sodium level was found to be decreased significantly (P=0.0001) in both studied experimental groups as compared to the control group. Level of potassium and chloride were also decreased significantly against control. The results are representative of three animal series (mean ± S.E.M.).
Figure 2:
Level of total proteins and albumin in sera. The level of total proteins (P<0.0001) and albumin (P<0.0001) showed a similar trend and was found to be decreased significantly in both studied experimental groups as compared to the control group. The results are representative of three animal series (mean ± S.E.M.).
Figure 3:
Level of WBCs, RBCs and Platelets in blood. WBCs, RBCs and Platelets all showed a significant negative change in the blood of both studied experimental groups as compared to the control group. The results are representative of three animal series (mean ± S.E.M.).
Figure 4:
Level of Hb and HCT in blood. Hb level was found to be decreased significantly (P<0.0001) in both experimental groups as compared to the control group. Level of HCT (P<0.0001) was increased significantly in Group 1 against control while Group 2 showed opposite trend to Group 1. The results are representative of three animal series (mean ± S.E.M.).
Figure 5:
Level of MCV, MCH and MCHC in blood. MCV level was found to be increased significantly (P<0.0001) in both studied groups as compared to the control. Level of MCH (P<0.0001) was decreased significantly in Group 1 against control while Group 2 showed opposite trend to Group 1. Regarding MCHC (P<0.0001) both experimental groups showed a significant negative trend against control. The results are representative of three animal series (mean ± S.E.M.).