Age and Sex Dependent Effects of Maternal Deprivation on Anxiety-Like and Depressive-Like Behaviors and Oxidative Stress in the Prefrontal Cortex of Rats
Age and Sex Dependent Effects of Maternal Deprivation on Anxiety-Like and Depressive-Like Behaviors and Oxidative Stress in the Prefrontal Cortex of Rats
Abdeljabbar Nassiri1, Mouloud Lamtai1*, Inssaf Berkiks1,2, Hajar Benmhammed1, Sidi Mohamed Coulibaly1,3, Miloud Chakit1, Laila Ibouzine-dine1, Abdelhalem Mesfioui1, Aboubaker El-Hessni1
Behavioral performances of adolescent, young adult and adult females and male rats in the open field test. A – Total amount time spent in the center (TCA); B – Number of return into center area (NRC), C – Number of total squares crossed (NTS). The symbols *, # and $ denote significant differences compared to control, or to gender counterparts, or between different age groups, respectively. The significance level is 0.05.
Behavioral performances of adolescent, young adult and adult females and male rats in to the elevated plus maze. A – Time spent on the Open Arms (TOA); B – Entries into Open Arms (EOA); C – Total Entries into the Arms (TEA). The symbols *, # and $ denote significant differences compared to control, or to gender counterparts, or between different age groups, respectively. The significance level is 0.05.
Effect of maternal deprivation on depression-related behavior of adolescent, young adult and adult females and male rats in the forced swimming test. TIM: immobility time. The symbols *, # and $ denote significant differences compared to control, or to gender counterparts, or between different age groups, respectively. The significance level is 0.05.
Effect of maternal deprivation on nitric oxide (NO) in the prefrontal cortex of adolescent, young adult and adult females and male rats. The symbols *, # and $ denote significant differences compared to control, or to gender counterparts, or between different age groups, respectively. The significance level is 0.05.
Effect of maternal deprivation on thiobarbituric acid reactive substances (TBARS) content in the prefrontal cortex of adolescent, young adult and adult females and male rats. The symbols *, # and $ denote significant differences compared to control, or to gender counterparts, or between different age groups, respectively. The significance level is 0.05.
