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Case Report · Volume 4, Issue 1, Pages 11–16, 27 April 2016 · Open Access

Multicentric B-cell Lymphoma and Disseminated Atherosclerosis in a Gelding

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Journal:
Research Journal for Veterinary Practitioners
Published:
27 April 2016
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From the article

  • Necropsy and histopathology revealed multicentric lymphoma involving spleen and abdominal lymph nodes, disseminated atherosclerosis of vena cava, aorta and myocardium and metastatic calcification.
  • Based on histopathological and immunohistochemistry, this case was diagnosed as multicentric low grade B-cell lymphoma.
  • In conclusion, this present case a horse suffered from multicentric B-cell lymphoma associated with atherosclerosis and metastatic calcification was noted.
  • Neurolymphomatosis in three horses with multicentric T-cell-rich B-cell lymphoma.

Selected from the article's own text.

Abstract

Jedsada Siripoonsub1, Sirintra Sirivisoot1, Sitthichok Lacharoje2, Somporn Techangamsuwan1, Anudep Rungsipipat1*

1Companion Animal Cancer Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok – 10330; 2Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok – 10330, Thailand.

Abstract | A 5-year old, 258-kg-weight, mixed thoroughbred gelding was found acute death with abdominal enlargement caused by hemorrhagic strangulated enteritis and colic. Necropsy and histopathology revealed multicentric lymphoma involving spleen and abdominal lymph nodes, disseminated atherosclerosis of vena cava, aorta and myocardium and metastatic calcification. Immunohistochemistry was performed in order to categorize immunophenotype of T-cell and B- cell lymphoma. This case was diagnosed as multicentric low grade B-cell lymphoma. In addition, pathogenesis of lymphoma associated with disseminated atherosclerosis of this case was discussed. 

Keywords | Atherosclerosis, B-cell lymphoma, Equine, Multicentric lymphoma

ETHICALLY APPROVED

This article does not contain any studies with human participants or experimental animals performed by any of the authors.

CONFLICT OF INTERESTS

The authors declare that they have no financial or personal relationship(s) which may have conflicts of interests them in writing this article.

ACKNOWLEDGEMENTS

This work was supported by Companion Animal Cancer Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok – 10330, Thailand.

AUTHOR’S CONTRIBUTION

All authors contributed equally in all details of this manuscript.

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