Oral cancer is widely spreading throughout Asia. This study focused on the prevalence of oral cancer in Pakistan from 2010 to 2016. Data for oral cancer cases was collected from the country's numerous cancer registries and cancer treatment facilities. Age and gender factors were analyzed in the data. For the given time, prevalence, incidence, and rate of age-standardized illness were determined. Data analysis indicated that oral cancer prevalence in Pakistan is increasing year after year, with the growth being particularly pronounced in the country's male population. From 2010 to 2016, the overall prevalence was 0.1 percent. The most common age of diagnosis for oral cancer was 45-65 years, and the standardized cancer incidence rate was 633.411 i.e. 8/1000000 with a confidence interval of 95%. The study concluded that oral cancer is significantly increasing in Pakistan, and there is a dire need to address this problem. In addition, we recommend the development of an appropriate nationwide system of cancer registry.