The sable was one species of holarctic carnivores and it was mainly in Russia, China, and Japan. There have little information about gastrointestinal parasite and bacterium of the sable, but it was important for its health. Five parasitic species and two hundreds thirty four gut bacteria (genus) of the sable were detected by the saturated NaCl floating and next sequencing methods. The parasites were Capillaria sp., Baylisascaris devosi, Echinochasmus sp., and two Coccidianspecies. The Echinochasmus sp. andtwo Coccidian species were first time found either in sable or in other martens. The 434 genus of bacteria, belong to 30 phylum, the more popular bacteria were Proteobacteria (33.54%), following by Firmicutes (18.58), Acidobacteria (12.82%), Actinobacteria (9.27%), Bacteridetes (5.44%), Crenarchaeota (4.58%), Fusobacteria (2.66%), Verrucomicrobia (2.29%), Gemmatimonadetes (2.18%) and Planctomycetes (1.39%), and they were more than 92.75%. The gut bacteria of the sable have more diversity than Siberian tiger, panda, horse, and human, and it may originate from the more divertible diet of the sable.