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Heat Shock Proteins and Cytochrome P450 1a1 Expression as Biomarkers of Exposure to Bisphenol A in Catla catla

Heat Shock Proteins and Cytochrome P450 1a1 Expression as Biomarkers of Exposure to Bisphenol A in Catla catla

Mehwish Faheem1*, Maleeha Rafeeq1, Aisha Majeed1 and Saba Khaliq2

1Department of Zoology, Government College University, Lahore
2Department of Physiology and Cell Biology, University of Health Sciences, Lahore

*  Corresponding author: mehwishfaheem@gcu.edu.pk

 

 

Fig. 1.

Liver heat shock proteins (70 and 90), cyp1A1 expression of adult female Catla catla exposed to graded concentration of BPA for 14 days. Gapdh, tbp used as reference control; M, marker; S1, control; S2, 10 μg/I BPA; S3, 100 μg/I BPA; S4, 1000 μg/I BPA.

Fig. 2.

Relative gene expression of the cytochrome p450 1a1 gene normalized tbp and gapdh (A) and heat shock protein 70 and 90 normalized to mean of three selected gene (gapdh, tbp) (B) in liver of Catla catla (n=3) after 14 days of exposure to graded concentration of BPA. Data expressed as mean fold change ±S.E.M. Different letters indicate significant differences among groups. P<0.05.

Pakistan Journal of Zoology

February

Vol. 52, Iss. 1, Pages 1-424

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