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HBV and HCV Seroprevalence in Hospital Admissions for Thalassemia Major in Bengbu, China

HBV and HCV Seroprevalence in Hospital Admissions for Thalassemia Major in Bengbu, China

Jun Zhang1*, Xiaocao Xu2 and Min Cao2

1Department of Blood Transfusion, The First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China
2School of Laboratory Medical, Bengbu Medical College, Bengbu, 233030, China
 
* Corresponding author: zhangjun027x@163.com

ABSTRACT

Patients with thalassemia major are exposed to a wide range of blood transition viruses that among them hepatitis B and C viruses are in high significance. This study investigates the seroprevalence of HBV and HCV in hospital admissions for thalassemia major in Bengbu, China. This study is a cross-sectional study in which information was extracted and collected from patients’ records, including gender, age, number of blood transfusions per year, HBs-Ag, HCV-Ab and Anti-HBs. The study included 630 thalassemia major patients who received regular blood transfusions at a hospital in Bengbu, China. We found that out of 630 patients of the study, there were three HBs-Ag positive, so the prevalence of HBV in this study is 0.5%. The prevalence of HCV-Ab positive was 7.1 and these individuals had a significantly older mean age than those with HCV-Ab negative. In 89.8% of patients the HBs-Ab titer was more than 10. Due to the progress of screening and selection of blood donors the prevalence of HBV infection in high-risk patients has sharply decreased in recent years. Vaccination is one of the most important protective factors in this group of the population. Therefore, administration of a reminder dose based on antibody titer is recommended in these individuals.

 

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Pakistan Journal of Zoology

August

Vol. 54, Iss. 4, Pages 1501-2001

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