Paulo Eduardo Brandao
...antivirals in inhibiting rabies virus intracellular cycle both in vitro and in vivo, and the high failure rate of this treatment in human patients, the use of RNA interference (RNAi) for Post-transcriptional Gene Silencing (PTGS) has witnessed an increasing interest from those concerned with a cure for rabies, inspired on the success obtained for other viral diseases. This review is intended to present the current situation ...
Uzma Farid Durrani1,*,Sagar Mal Goyal2, Asim Khalid Mahmood1,Cathleen Hanlon3, Susan Moore3, Muhammad Waqas1 and Raheela Akhtar4
... (< 3 months age), in rabies endemic Lahore city of Pakistan, to evaluate their maternal rabies virus neutralizing antibody titer (mRVNA). All puppies were whelped by dams regularly vaccinated with high quality inactivated rabies vaccines. Rapid Fluorescence Focus Inhibition Technique (RFFIT) revealed mRVNA titer (>0.5 IU/mL) in 29 puppies while 48 puppies showed mRVNA titer less tha...
Zain ul Abidin1, Aisha Khatoon2, Abdul Whab Manzoor1,*, Nida Arooj1, Sajjad Ali1 and Muhammad Numan1
...d screening of suspected rabies samples of cow and mule. Clear behavioral changes along with paralysis of tail and hind legs were noticed in the mice of both groups between 11-15 days post inoculation while all the mice were found dead between 15-18 days post inoculation in mouse inoculation test (MIT). Reverse transcriptase-polymerase chain reaction (RT-PCR) performed for both samples gave a product of 443-bp amplifying the highly conserved “N”-re...
Huanxin Zhang1,2, Hongshuo Tang3, Jun Chen1, Yu Zang1,2, Xuexi Tang1,2,* and Ying Wang1,2,*
...odons were identified in rabies virus associated TLRs (TLR3 and TLR7); we speculated that the virus associated TLRs were mainly under purifying selection. In conclusions, the TLR genes were mainly shaped by purifying selection, and the limit number of positive selection codons may be resulted from ancient functional adaptation in the carnivores.
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Yanni, M. I1; Hanaa A. Ahmed2; Lamyaa, A. Ahmed1; Hanan, A. Fahmy3 and Ibrahim, E.M.4 Aggour, M. G.3
Amthal Ahmed Fouad1, Basem Mohamed Ahmed2, Momtaz Abdelhady Shahein1, Hussein Aly Hussein2*
...p>Background: Lyssavirus rabies is a major global zoonosis and is endemic in Egypt. Rabid dogs are the prime source for human and livestock Lyssavirus rabies (RABV) exposure with almost 100% case fatality. While all lyssavirus rabies genetic data -including whole genomes- from Egypt are clustered within a unique lineage (Africa-4 lineage of the cosmopolitan clade), no report provided detai...
Saloua Ziani1*, Khalid Sohaib2 , Youssef Lhor3, Ikhlass El Berbri4, And Ouafaa Fassi Fihri4
...tional movement of pets, rabies-free countries require a rabies quantification before importing animals, which varies significantly. The objective of this study is to investigate the reasons for variations in antibody titers in dogs. Data from 848 dogs exported from Morocco was collected. The results revealed that too-old dogs (over six years) or too young (under four months) are also less likely to respond to vaccination th...
Morcos Ibrahim Yanni1* and Eid Elsaid Abdelaziz2
...amino acids variation of rabies virus isolates from the brain tissues of three dogs from 2017 to 2019 at the genetic level of the N and P genes from three governorates of Delta region in Egypt with earlier isolates, locally used vaccinal strains and other used strains internationally. Ten brain tissues from confirmed rabid cases in three governorates; Dakahleya (3), Alexandria (4); and Beheira (3) were diagnosed using viral cell culture and Direct Fluorescent ...
Mazharul A. M. 1, Md. S. Sarwar ,M. Nurullah 2, Keshab K. Adhikary I and M. Rahmatullah 1
...easles, chicken pox, and rabies are fairly common occurrences throughout Bangladesh. Since the population of the country is predominantly rural without proper access to modern medical facilities, they rely on traditional medical practitiofiers (Vaidyas) and plant-based formulas to treat such viral diseases. Ethnobotanical surveys were carried out amongst three ethnic groups (Garo, Khasia and Santal) and five districts of Bangladesh to identify medicinal p...
Kalsoom Abdulrazaq1*, Bisma Arif1, Rimsha Mehboob2, Asma Mehboob3
...iseased animals, such as rabies, and through bites, or indirectly through exposure to contaminated surroundings and contaminated food. Vectors, such as mosquitoes or ticks, play a role in the transmission of diseases like West Nile fever and Lyme disease, respectively. Several factors impact diseases caused by zoonoses, and the convergence model classifies these components into major areas, including the interaction between domestic animals, wild animals, and ...
Karima Akool Al-Salihi1*, Luay Jumaah Jihad2, Abbas Najm Aldin Saleh3
...go hemorrhagic fever and rabies in humans. The participants (187) responded at a rate of 98.1%. The undergraduate students and graduated veterinarian percentages were 79.67% and 20.32%, respectively. Online study materials were accessed via Google Classrooms, University platforms, You Tube, and Slide Share. Moreover, Google Classroom, Telegram, WhatsApp, Viber, Zoom, and FCC were the tools for lectures and communication with lecturers. A variation appeared in ...
Muhammad Wasif Gulzar*, Riffat Maqsood, Muhammad Zain, Muhammad Suleman, Tayyab Ur Rehman, Sana Asif, Abdul Wadood and Jawad Hussain
...ats, and foxes are major rabies reservoirs. The disease is primarily spread by the bite of a rabid animal and the saliva of an infected host. The incubation period (average 2-3 months) varies greatly, with periods ranging from 2 weeks to 6 years. Neuropathological lesions are typically modest, despite significant neurologic symptoms and a deadly prognosis. The Rabies virus uses several strategies to circumvent the host&rsquo...
Nguyen Phi Bang1,2*, Nguyen Thi Hanh Chi1,2, Ngo Thuy Bao Tran1,2, Nguyen Thi Bich Hanh1,2, Nguyen Ba Trung1,2, Le Thi Thuy Hang1,2
...ext-align: justify;">The rabies vaccine has been a crucial tool in controlling this hazardous disease globally. Its effectiveness is influenced by various factors, including the vaccine’s quality, the animals’ health, and the vaccination method. In An Giang (Vietnam), state veterinary officials use the Rabisin vaccine, which prevents rabies in pets when given to healthy canines by manufacturer’s recommendat...
