Hina Abrar1,2, S.N.H. Naqvi1,*, Muhammad Rashid Ahmed3, Asma Basharat Ali3 and Hina Yasin1,2
...nvestigate the effect of propranolol to reduce hepatoxicity of carbamazepine (CBZ). Animals were divided into three groups; control, CBZ administered group (200 mg/Kg for 10 days) and CBZ plus propranolol (30 mg/Kg for 10 days) treated group. Liver function test and histological evaluation by H and E staining and scanning electron microscopy (SEM) was carried at the end of dosing by using standard procedures. Serum level of ...
Zongliang Li1, Rongxin Ma2,*, Yan Wei1 and Jianghua Zuo3
...up (taking one tablet of propranolol) and the combination treatment group (topical application of timolol maleate and 32P application). mRNA expression of VEGF and TGF-b was increased in the conventional treatment group compared with the combination treatment group (P<0.05). The protein expression of bFGF and IL-6 in the combined treatment group was lower than that in the conventional treatment group (P<0.05). The conventional treatment group 30 (75.00%)...
Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*
...del (hypoxia), positive (propranolol 30 mg/kg + hypoxia), and three G. straminea ethanol extracts dose groups (10, 5 and 2.5 g/kg respectively + hypoxia), administered intragastrically once a day for 14 consecutive days. After that, multiple hypoxia experiments were conducted including soda lime normobaric hypoxia test, sodium nitrite poisoning test, isoproterenol poisoning test, and acute cerebral ischemic hypoxia test. Subsequently, the content of superoxide...
Hina Abrar1*, Hina Yasin1, Hira Naeem2, Rabia Bushra1, Shaukat Mahmood2 and Kaneez Fatima3
Eman Wahsh1, Tarek M Ibrahim2, Mirna E. ElAwady3*
...ipine, and beta-blocker, propranolol, are currently investigated for their possible anxiolytic effects. Anxiolytic properties of CCBs are attributed to inhibition of brain calcium transportation. Propranolol reduces the physical signs of anxiety by blocking adrenergic neurotransmitters. Currently, Vogel conflict paradigm was applied to measure anxiety and validated by using anxiolytic agent, diazepam, and anxiogenic drug, ca...
