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Effect of Variable Kisspeptin Doses on Prostatic Citric Acid Levels in Male Mice

Faiqah Ramzan*¹ and Muhammad Haris Ramzan²

...ollowing intraperitoneal kisspeptin treatment. However, effects of kisspeptin administration on the levels of prostatic citric acid remain elusive till date. The present study, therefore, addresses the effects of 12 day administration of kisspeptin on prostatic citric acid levels in male mice. Kisspeptin-10 was administered intraperitoneally in different...

Changes in Kisspeptin, Growth and Thyroid Hormones in Thalassemic Patients of Pubertal Age Group

Shazia Ali, Hizb Ullah and Sarwat Jahan*

...sub>TSH (μIU/mL), and kisspeptin (ng/ml) was done. BMI and hemoglobin were significantly reduced (P<0.001), while serum ferritin were significantly increased (P<0.001) in all four thalassemic groups on comparison with control. Kisspeptin levels were significantly reduced in ≤13 years female (P<0.001). While significantly high levels were observed in >13 years of male (P<0.01). T₃ levels were s...

Effects of Novel Oral and Plasmid-Injected KISS1 DNA Vaccines on Immunocastration and in Inhibiting Mutton Odour of Male Goats

Yan-Guo Han, Jia-Yuan Wu, Ri-Su Na, Wei-Jiang Si, Yu-Qin Han, Yan Zeng, Yong-Ju Zhao and Yong-Fu Huang*

...ion for the detection of kisspeptin antibodies and testosterone by indirect enzyme-linked immunosorbent assay. Scrotal circumference was detected from week 0 to week 14 after primary immunisation, and the testes were weighed at week 14 after primary immunisation after slaughter. The concentrations of 4-methyloctanoic acid and 4-methylnonanoic acid in waist subcutaneous adipose tissue were detected using gas chromatography. Immunisation of oral and plasmid-inje...

Dose Dependent Effect of Kisspeptin-10 Administration on Spermatogenesis and Hypothalamic Pituitary Gonadal Axis in Prepubertal Rats

Faiqah Ramzan^1,2,*, Irfan Zia Qureshi² and Muhammad Haris Ramzan³

...ze: small;">Discovery of kisspeptin and its receptor has enhanced our understanding of the neurobiological mechanisms that govern the pituitary-gonadal-axis. However, in sexually immature male mammals, the maturation of gonads is not clear yet. The current study tested the hypothesis that continuous kisspeptin administration suppresses gonadotropin and testosterone release and spermatogenesis. Intraperitoneal