Articles
185 open-access articles · page 8 of 10
Mini-ReviewReporter Classical Swine Fever Virus: A Powerful Tool to Study Virus Biology
Yongfeng Li, Mo Zhou, Xiao Wang, Libao Xie, Hua-Ji Qiu
Classical swine fever virus (CSFV) is generally a noncytopathogenic virus in cell cultures. The development of reporter CSFV has provided an excellent option to directly detect viral replication without the use of secondary labeling. This mini-review discusses…
2 May 2016
Research ArticleVisualization of Borna Disease Virus Protein Interactions with Host Proteins using in situ Proximity Ligation Assay
Jonas Johansson Wensman1*a, Karl-Johan Leuchowius, Jiting Yan, Anna-Lena Berg, Liv Bode, Hanns Ludwig et al.
Borna disease virus type 1 (BDV) comprises highly conserved neurotropic non-segmented negative strand RNA-virus variants causing neurological and behavioral disorders in a wide range of mammalian animals, possibly including humans. Viral persistence in the bra…
20 Mar 2016
ReviewReference Genes: Essential Criteria for Assessment of the Real-Time PCR Based Virus Detection in Plants Virology
Rongfei Lu, Zhiyang Liu, Peng Fang, Guangyi Chen, Feng Sun, Yongjian Fan et al.
Real-time quantitative PCR (RT-qPCR) plays an important role in the current field of virus detection and disease dynamics. The validity and the reliability of generated data can be enhanced significantly appropriate measures. As a standard for the relati…
17 Mar 2016- Review
A Virus-like Particle Vaccine Against Infectious Bursal Disease Virus: Potential Uses and Applications
Kang-Seuk Choi
Infectious bursal disease (IBD) virus-like particles (VLPs) comprising only viral capsid proteins mimic the naive configuration of authentic IBD virus particles. The VLPs show intrinsic immunogenicity and a high safety profile. Thus, VLPs are considered…
13 Mar 2016 - Review
Targeting Cellular and Virus Encoded LncRNAs: Emerging Opportunities for Novel Anti-influenza Therapies
Shubhada K Chothe, Bhushan M Jayarao, Suresh V Kuchipudi
Long non coding RNAs (lncRNA) contribute to a large proportion of the cellular RNA and are involved in regulating a plethora of biological and pathological processes. There is a strong evidence to suggest the association of differential regulation of non…
24 Jan 2016 - Review
Metagenomics-driven Virome: Current Procedures and New Additions
Claudia Kohl, Andreas Nitsche, Andreas Kurth Email: kohlc@rki.de
Next generation sequencing (NGS) opened up a plethora of new research possibilities in biology and medicine. Metagenomics is one of these emerging NGS applications and offers the opportunity to study i.e. whole ecosystems. Basically, the metagenomics approach…
14 Jan 2016 
Research ArticleSpatial and Seasonal Distribution of Culicoides Species in Morocco in Relation to the Transmission of Bluetongue Viruses
Youssef Lhor, Mounir Khayli, Mohamed Bouslikhane, Mehdi El Harrak, Ouafaa Fassi Fihri2 Email: y.lhor@yahoo.fr
The present study was undertaken to examine the data collected from a retrospective surveillance of Culicoides (Diptera: Ceratopogonidae) biting midge vectors from April 2009 to March 2010 in Morocco. In order to assess the implementation of integrated co…
12 Dec 2015
Research ArticleEfficacy of Disinfectants against Egyptian H5N1 Avian Influenza Virus
Mohammed A. Rohaim, Rania F. El-Naggar, Abdulrahman M. Gamal, Elshaimaa Ismael, Mohamed M. Hamoud, Sherif T. Moubarak et al.
Poultry industry in Egypt is facing various management problems along with infectious diseases including avian influenza (AI). Biosecurity measures, controlling poultry movements and inactivated vaccines were devised to combat the spread of highly pa…
5 Dec 2015
Research ArticleNonpolio Enterovirus-C (NPEV-C) Strains Circulating in South- Western Nigeria and their Contribution to the Emergence of Recombinant cVDPV2 Lineages
Temitope Oluwasegun Cephas Faleye, Johnson Adekunle Adeniji
Recently, we showed that the nonstructural region of some of the cVDPV2 lineages described in Nigeria between 2005 and 2011 originated from NPEV-Cs circulating in Northern Nigeria. Here, we further investigate whether NPEV-Cs circulating in south-western Niger…
22 Nov 2015
Short CommunicationSeroprevalence of Bluetongue and Associated Risk Factors in Costa Rican Sheep Flocks
Rodolfo Villagra-Blanco, Gaby Dolz, Danilo Montero-Caballero, Juan Jose Romero-Zuniga
Blood samples from a total of 359 sheep from 15 farms were analysed for the presence of antibodies against bluetongue virus (BTV) by commercial enzyme-linked immunosorbent assay (ELISA). Antibodies were detected in 290 sheep from fourteen different flocks, dis…
22 Nov 2015
Research ArticleDetection of Hepatitis E Virus among HIV Infected Individuals in Ogbomoso, South-western Nigeria
Oladipo Elijah Kolawole, Oloke Julius Kola, Awoyelu Elukunbi Hilda, Olasunmibo Oluwatobi Gabriel, Ogunyale Tolulope Temitope E-mail | koladipo2k3@ yahoo.co.uk
Hepatitis E virus is a foodborne and waterborne virus commonly transmitted faecal-orally and through the transplacenta. Hepatitis E virus is one of the viruses that causes acute and self-limiting infection with a high risk of developing chronic hepatitis in im…
31 Oct 2015
CommentaryIntra-Host Bayesian Phylogeography Linking Viral Evolution and Pathogenesis Comes to an Age
Brittany D. Rife, Marco Salemi, E-mail | salemi@pathology.ufl.edu
Bayesian phylogeographic analysis has recently been at the forefront of understanding epidemiological processes through the reconstruction of evolutionary history and spatial dissemination of pathogens. Infection of a single host can be viewed simila…
3 Oct 2015- Review
Current Progress and Future Perspectives of Controlling Japanese Encephalitis Virus
Guoyi Li, Haiyan Tong, Jiansheng Chen, Jinliang Wei, Xiaoming Zhao, Guoping Zhang et al.
Japanese encephalitis (JE) is an arthropod-borne disease causing dreadful central nervous system signs and high mortality in adults and children. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of East…
3 Oct 2015 - Commentary
Tamiflu-What we Know About its Ups and Downs
Josef D. Jarhult
The pros and cons of the anti-influenza drug oseltamivir (Tamiflu®) have been intensely debated lately. This article aims to sum up what is known about positive and negative effects of the drug. The available data suggests that oseltamivir treatment of unc…
12 Jun 2015 
Mini-ReviewRT-NASBA: An Ideal Approach for the Detection of Diarrhoea-Related Viruses
Hai-Bo Wang, Qiu-Hua Mo, Ze Yang
RT-NASBA is a rapid and sensitive diagnostic system, which combines nucleic acid sequence-based amplification (NASBA) and molecular beacon technique. Recently there have been two major progresses in the field, in which RT-NASBA technique was applied for the de…
9 Jun 2015- Commentary
Antiviral Roles of Artificial microRNAs
Huaichang Sun
Many RNA viruses undergo rapid mutations which compromises the immune protection of conventional vaccines. RNA interference (RNAi) has becoming a feasible strategy against various virus infections. Recently, a significant advance in RNAi technology is the use…
9 Jun 2015 - Review
Innate Immune Responses against Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus
Shen Yang, Guang-Zhi Tong
Antiviral innate immunity plays a central role at the early stage of viral life cycles. The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is a major concern for the swine industry and causes high degrees of morbidity and mort…
31 May 2015 - Mini-Review
Harnessing the Power of miRNAs in Influenza A Virus Research
Leonard Izzard, John Stambas
The application and use of miRNA-based technology in influenza research is rapidly expanding. miRNAs are currently being used to manipulate pathogenicity and immunity and as biomarkers for disease severity.
24 May 2015 - Preview
Louping Ill Virus (LIV) in the Far East: A Perspective
Galina N. Leonova, Ilya G. Kondratov, Sergei I. Belikov
This study focused on finding, culturing, and identifying the biological and genetic characteristics of three Louping ill virus (LIV) strains in the south of the Russian Far East isolated from Ixodes persulcatus ticks and one strain was isolated from the blood…
17 Mar 2015 - Preview
NDV Induced Immune-Pathology in Chickens
Hu Zenglei, Xiufan Liu
Virulence and pathogenicity of Newcastle disease virus (NDV) is one of the major determinants for the clinicopathological manifestations in infected hosts. Recent studies showed that the host innate immune responses to infection play important role in the path…
17 Mar 2015