Unraveling Renal Complexities in Thalassemia Major: A Comprehensive Nephrological Inquiry in Central Punjab, Pakistan
Unraveling Renal Complexities in Thalassemia Major: A Comprehensive Nephrological Inquiry in Central Punjab, Pakistan
Muhammad Waqas1*, Razia Bashir1, Khadija Munir1 and Muhammad Arshad2
ABSTRACT
This research investigates the intricate nexus between thalassemia major and renal dysfunction in Central Punjab, Pakistan. A comprehensive analysis was conducted on a diverse cohort of beta-thalassemic patients to explore the prevalence and factors influencing renal profiles. The study encompassed demographic factors, family history, and caste systems, shedding light on their associations with beta-thalassemia. Furthermore, gender and age-specific assessments were performed, focusing on serum creatinine and urea levels to provide a nuanced understanding of renal function. The findings revealed a higher prevalence of beta-thalassemia in the 11-20 years age group, emphasizing the critical role of adolescence and early adulthood in the manifestation of this genetic disorder. Family history emerged as a significant factor, with patients having positive family histories showing a higher prevalence. Caste-based analysis highlighted variations in prevalence, with Arains and Rajpoot exhibiting the highest rates. Renal profile assessments, including serum creatinine and urea levels, indicated stable renal function across genders and age groups. No significant variations were observed, reaffirming the stability of renal parameters in beta-thalassemic patients. The study contributes valuable insights for targeted healthcare strategies, genetic counseling, and awareness programs in managing thalassemia major in the Central Punjab population.
To share on other social networks, click on any share button. What are these?
