The Levels of Prostate Specific Antigen and Leptin Hormone in Patients with Prostate Cancer
The Levels of Prostate Specific Antigen and Leptin Hormone in Patients with Prostate Cancer
Nesreen Ahmed Nasser1, Anas H. Sadek2, Bayadir Abdulhussein Mahmeed3, Osama Akram Mohsein4*
ABSTRACT
Background; Prostate cancer ranks as the sixth most commonly diagnosed cancer and is the most commonly diagnosed cancer among males worldwide. Surveillance PSA testing remains a controversial topic, although MRI scans, prostate tissue biopsies, and prostate-specific antigen (PSA) testing are the main diagnostic methods. Aims of the study: Estimating the levels of prostate cancer antigen and leptin in patients with prostate cancer and their role in the development of the disease. Methodology; The study included 35 men suffering from prostate cancer and 35 healthy men as a control group. Samples were collected at Al-Kadhimiya Hospital for the period between 1/11/2023 and 1/3/2024, and 5 ml was withdrawn from each participant and placed in a gel tube. prostate-specific antigen (PSA) and leptin levels were examined using enzyme-linked immunosorbent assays. Result; The results showed that there was no statistical significance in age or body mass index. The results also showed an increase in blood sugar, leptin, PSA, cholesterol, triglycerides, GOT, GPT, urea, and creatinine in the patient group compared to the control group. Conclusions; The increase in all biomarkers in patients with prostate cancer suggests the importance of intensifying studies on this type of cancer because of its future risks.
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