The Comparison of Moringa oleifera Seeds Oil and Fish Oil in Organ Weight and Blood Haematological Profile in Subchronic Male Mice
The Comparison of Moringa oleifera Seeds Oil and Fish Oil in Organ Weight and Blood Haematological Profile in Subchronic Male Mice
Andi Hiroyuki1,2,*, Refina Sastya Qomariyuti1, Najmah Nur Islami3, Vanessa Ayu Sumirat4, Neni Anggraeni5, Mas Rizky A.A Syamsunarno2,6
ABSTRACT
Livestock productivity can be increased by promoting growth using feed supplements such as fish oil containing omega 3, 6 and 9. These ingredients can also be found in Moringa seed oil which is cheaper and easier to find than fish oil. Omega 3 and 6 can increase dietary palatability thereby increasing feed intake which helps increase body weight which is correlated with organ weight. Based on this, a study was conducted that aims to compare the effect of Moringa seed oil and fish oil on organ weight and blood hematological profiles of mice. The study used 24 male mice of the DDY strain which were divided into three groups, namely the control group (Na-CMC-1%), KSO (moringa seed oil), and Omega-3 (fish oil). Mice were checked for temperature, GDP, and body weight at the beginning and end of the experimental period after 6 weeks. After that, the mice were sacrificed and blood samples were taken for hematological examination and the heart, liver, white fat tissue, and kidneys were weighed. The results showed that the average heart weight (0.120 grams) and white fat tissue (0.145 grams) decreased in the KSO group, as did RBC (8.285×106/μl), WBC (2,943×103/μl) and platelets (506 ,5×103/μl), but statistically there was no significant difference in hematological parameters, body temperature, GDP, body weight and liver and kidney weight p(> 0.05). However, there was a difference in heart weight and white fat tissue p(<0.05). In conclusion, Moringa seed oil can affect organ weight and blood hematological profiles like fish oil, but further research is needed to ensure that Moringa seed oil can be used as an alternative to fish oil substitute feed supplements.
Keywords | Organ weight, Moringa oil, Fish oil, Hematology profile, Feed supplement.
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