Studies on the Physical Parameters for Cephalosporin Biosynthesis from Acremonium chrysogenum by Submerged Fermentation
Umar Farooq Gohar1, Hamid Mukhtar1,*, Ali Nawaz1, Ikram-ul-Haq1 and Asad Mehmmood2
1Institute of Industrial Biotechnology, GC University, Lahore-54000, Pakistan
2 School of Chemistry, University of New South Wales, Australia
* Corresponding author: hamidwaseer@yahoo.com
Fig. 1.
Optimization of the incubation temperature for the production of cephalosporin by Acremonium chrysogenum in shakes flasks. All the values are means of three parallel replicates. Y-error bars indicate the standard error from mean. Fermentation conditions: incubation period= 144 h.
Fig. 2.
Optimization of incubation period for the production of cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y- error bars indicate the standard error from mean. Fermentation conditions: incubation temperature = 30°C, initial pH = 6.6.
Fig. 3.
Effect of the initial pH of culture medium on the production of Cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y-error bars indicate the standard error from mean. Fermentation conditions: incubation period=144 h; incubation temperature = 30°C.
Fig. 4.
Effect of inoculum of various sizes and ages on the production of cephalosporin by Acremonium chrysogenum in shake flasks. All the values are means of three parallel replicates. Y- error bars indicate the standard error from mean. Fermentation conditions: Incubation period = 144 h; incubation temperature = 30 °C; pH = 6.5. C, amount of cephalosporin; DMM, dry mycelial mass.