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Sheep Placental Extract Improves Memory and Exercise Performance in Senescence-Accelerated Mice

Sheep Placental Extract Improves Memory and Exercise Performance in Senescence-Accelerated Mice

Hafiz Muhammad Farooq Yaqub1, Sehrish Firyal1, Ali Raza Awan1, Muhammad Tayyab1, Rashid Saif2, Muti ur Rehman3, Muhammad Wasim1*

1Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, Pakistan
2Decode Genomics, 323-D, Punjab University Employees Housing Scheme, Lahore, Pakistan 
3Department of Pathology, University of Veterinary and Animal Sciences, Lahore, Pakistan
 
*      Corresponding author: muhammad.wasim@uvas.edu.pk

Fig. 1.

Effect of SPE on passive avoidance test in SAMP8 mice. (A) Male (B) Female. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).

Fig. 2.

 Effect of SPE on active avoidance test in SAMP8 mice. (A) Male (B) Female. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).

Fig. 3.

SPE increases the forelimb grip strength in ageing mice. (A) Male (B) Female. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).

Fig. 4.
SPE increases exercise performance in male senescence-accelerated mice. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).
Fig. 5.

SPE increases exercise performance in female senescence-accelerated mice. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).

Fig. 6.

Effect of SPE on liver glycogen and serum lactate in SAMP8 mice. (A) Male (B) Female. Data were expressed as the mean ± SEM and analyzed by one-way ANOVA. Groups with different letters indicate significant differences among each group (p<0.05).

Pakistan Journal of Zoology

June

Pakistan J. Zool., Vol. 56, Iss. 3, pp. 1001-1500

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