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Rivaroxaban Reduces Cerebral Hemorrhage in Mice with TPA Ischemic Stroke after Thrombolysis by Down-Regulating PAR-1 and PAR-2

Rivaroxaban Reduces Cerebral Hemorrhage in Mice with TPA Ischemic Stroke after Thrombolysis by Down-Regulating PAR-1 and PAR-2

Sen Ye1, Jiangang Pang2 and Xiuli Wang3*

1Medical Records Department, Jinan Central Hospital, 250013, China
2Medical Imaging Department, Yidu Ce ntral Hospital of Weifang, Weifang, 252500, China
3General Practice of Kuangshan Community Service Center, Jinan Ind People’s Hospital, Jinan, 250001, China
 
* Corresponding author: [email protected]

Fig. 1.
Representative photographs of intracerebral hemorrhage (ICH) show: W+tPA group has stronger intracerebral hemorrhage (arrow), R(L)+tPA group has weaker intracerebral hemorrhage, (R(H)+tPA group has stronger intracerebral hemorrhage (arrow), R(L)+tPA has weaker intracerebral hemorrhage, (R)+tPA group has stronger intracerebral hemorrhage (arrow), and R(H)+tPA group has weaker intracerebral hemorrhage (arrow). Scale: 2mm.
For details of groups, see Table I.
Fig. 2.

W+tPA group has stronger IgG staining in neurons and nerve fiber network, but the difference is insignificant between the four groups. Scale: 50mm. For details of groups, see Figure 1 and Table I. 

Pakistan Journal of Zoology

December

Pakistan J. Zool., Vol. 56, Iss. 6, pp. 2501-3000

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