Protective Mechanism of Velvet Antler Polypeptide on Myocardial Ischemia-Reperfusion Injury in Rats
Protective Mechanism of Velvet Antler Polypeptide on Myocardial Ischemia-Reperfusion Injury in Rats
Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*
Fig. 1.
ECG changes of rats under treatment in each group. A, normal rats; B, ligation ischemia; C, reperfusion 30 min after ligation ischemia.
Fig. 2.
LDH (A) and CK-MB (B) activities in serum of each group.
Note: ## p<0.01, compared with control group; ** p<0.01, compared with MIRI group.
Fig. 3.
MDA (A), SOD (B), GSH-Px (C) and CAT (D) activities in myocardial tissue.
Note: Compared with the control group, # p<0.05, ## p<0.01; Compared with MIRI group,* p<0.05, ** p<0.01.
Fig. 4.
H and E staining of myocardial tissue in each group (×300). A, Control group; B, MIRI group; C, DLZ group; D, MIRI + VAP-H group; E, MIRI + VAP-M group; F, MIRI + VAP-L group.
Fig. 5.
Effects of VAP on the expression of Nrf2 (A, B, D), HO-1 (A, C), NQO1 (A, E) in MIRI rats by Western blotting.
Note: Compared with Control group, ## p<0.01; Compared with MIRI group, * p<0.05, ** p<0.01.
February 2024
Pakistan J. Zool., Vol. 56, Iss. 1, pp. 01-501
