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Molecular Genetics of Aichivirus C (Porcine Kobuvirus) in China

Lei Chen, Ling Zhu, Zhi-Wen Xu, Wan-Zhu Guo


Animal Biotechnology Center, College of Veterinary Medicine of Sichuan Agricultural University, 46# Xinkang Road, Yucheng District, Ya’an, 625014, Sichuan province of P.R. China



Aichivirus C is a member of the Kobuvirus genus within the Picornaviridae family and is widely distributed in both healthy and diarrheic pigs from China. Due to the high detection rate in the severe diarrhea in China, Aichivirus C is thought to be a potential pathogeny of pig diarrhea. The review represented the discovery of Aichivirus C in China, and made a brief summary about molecular and epidemiology characterizations of Chinese Aichivirus C strains. Mutiple Aichivirus C strains and Aichivirus C variants are circulating in China. Recombination events were also observed in Chinese Aichivirus C strains. More further studies are needed to clarify the evolutionary features and pathogenicity of Aichivirus C.


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Hosts and Viruses


Vol.9, Pages 1-45


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