In-vitro Anticancer Activity of Copper (II) and Zinc (II) Complexes with Derived Schiff Base Ligands
In-vitro Anticancer Activity of Copper (II) and Zinc (II) Complexes with Derived Schiff Base Ligands
Qaisar Jamal1,Salman Ahmad1, Nazma Habib Khan1, Sobia Wahid1, Muhammad Ikram2, Sadia Rehman2, Syed Basit Rasheed1 and Akram Shah1,*
Fig. 1.
Structure of test complexes with Schiff base derived ligands: A, NM-3 Tetrakis(2-{(E)-[(2-{[(Z)-(2-hydroxynapthyl)methylidene]amino}phenyl)imino]methyl}phenol)Copper(II). Formula: C28H18CuN2O2, Mol. Wt: 478gms. B, NM-4 Tetrakis (2-{(E)-[(2-{[(Z)-(2-hydroxynapthyl)methylidene]amino}phenyl)imino]methyl}phenol)zinc(II). Formula: C28H18N2O2Zn; Mol. Wt: 480gms.
Fig. 2.
Percent inhibition by THP1 cells (A) PBLs (B) against four concentrations of NM3, NM4 and miltefosine.
December 2018
Vol. 50, Iss. 6, Pages 1999-2398
