Identification of Absorbed Constituents and their Metabolites Related to Estrogen-Like Activity of Total Glycosides of Cistanche deserticola in Rat Serum
Yang Hu, Jingxin Ding, Beilei Xu, Xiangming Sun, Guoyu Li, Hui Song, Zheng Zong and Wenlan Li*
College of Pharmacy, Harbin University of Commerce, Harbin 150076, China
Fig. 1.
Serum fingerprint of TGs collected at different time points. (A) positive ion mode; (B) negative ion mode. S1-S10 represent 0.25, 0.5, 1, 1.5, 2, 4, 6, 8, 10, 12 h, respectively.
Fig. 2.
Bivariate analysis of estrogen activity and common peaks in serum TGs collected at different time points. (A) positive ion mode; (B) negative ion mode.
*significant correlation (p <0.05) when absolute value of correlation coefficient was >0.3; ** extremely significant correlation (p <0.01) when absolute value of correlation coefficient was >0.5.
Fig. 3.
Grey relational analysis of estrogen activity and common peaks in serum TGs collected at different time points. (A) positive ion mode; (B) negative ion mode.
* correlation when the value of the correlation coefficient was >0.5.