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Identification of Novel Mutations in LCT-Gene of Pakistani Patients with Lactose Non-persistence

Identification of Novel Mutations in LCT-Gene of Pakistani Patients with Lactose Non-persistence

Maria Qibtia1, Muhammad Wasim1, Farzana Chowdhary1, Muhammad Tayyab1, Sehrish Faryal1, Ahmed Mansouri2, Zeeshan Ahmad2, Muhammad Hamid3 and Ali Raza Awan1,*

1Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Shaykh Abdul Qadir Jilani Road, Data Gunj Buksh Town, Lahore, Pakistan
2Max-Planck Institute for Biophysical Chemistry, Molecular Cell Differentiation Group, Am Fassberg 11, 37077 Göttingen, Germany
3University of Ulm, Energiewandlung und Speicherung, Albert Einstein Allee 47, 89081 Ulm, Germany

*      Corresponding author: arawan77@uvas.edu.pk

Fig. 1.

Molecular model of LCT-gene (NCBI) 2012.

Fig. 2.

Predicting molecular modeling of LCT-gene with alterations.

Fig. 3.

Exonic and intronic alterations in LCT-gene

Fig. 4.

Chromatograms of SNP in the LCT-gene promoter region.

Fig. 5.

Genetic variations in LCT-gene (McIntosh and Scheinfeldt, 2012).

Pakistan Journal of Zoology

August

Vol. 53, Iss. 4, Pages 1201-1601

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