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HLA System and its Participation in Recurrent Pregnancy Loss

HLA System and its Participation in Recurrent Pregnancy Loss

Laiba Ajmal1, Sidra Ajmal2, Maleeha Ajmal3, Gul Nawaz3, Rabail Hassan Toor4, Hooria Younas1, Tassaduq Hussain Sheikh5 and Raazia Tasadduq1*

1Department of Biochemistry, Kinnaird College for Women, 93 Jail Road, GOR 1, Lahore, Pakistan
2Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, United States
3Internal Medicine, Marshfield Clinic Health System, Marshfield, Wisconsin, United States
4School of Biological Sciences, University of Punjab, Quaid-I-Azam Campus, Lahore, 54590, Pakistan
5Department of Anatomy, Central Park Medical College, Lahore, Pakistan
* Corresponding author:

Fig. 1.

Modulation of maternal immune response by HLA-C is influenced by its interaction with the activating or inhibitory KIR.

Fig. 2.

Effect of interactions between HLA-E and NKG2 in normal pregnancy and pregnancy loss.

Fig. 3.

HLA-G, a mediator of cross-talk between EVT and maternal immune cells.

Pakistan Journal of Zoology


Vol. 54, Iss. 5, Pages 2003-2500


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